1fsg

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[[Image:1fsg.png|left|200px]]
 
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{{STRUCTURE_1fsg| PDB=1fsg | SCENE= }}
{{STRUCTURE_1fsg| PDB=1fsg | SCENE= }}
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===TOXOPLASMA GONDII HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH 9-DEAZAGUANINE, ALPHA-D-5-PHOSPHORIBOSYL-1-PYROPHOSPHATE (PRPP) AND TWO MG2+ IONS===
===TOXOPLASMA GONDII HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH 9-DEAZAGUANINE, ALPHA-D-5-PHOSPHORIBOSYL-1-PYROPHOSPHATE (PRPP) AND TWO MG2+ IONS===
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{{ABSTRACT_PUBMED_11188695}}
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==Function==
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[[http://www.uniprot.org/uniprot/HGXR_TOXGO HGXR_TOXGO]] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to the N(9) of hypoxanthine, guanine or xanthine.<ref>PMID:11188695</ref>
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{{ABSTRACT_PUBMED_11188695}}
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==About this Structure==
==About this Structure==
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1FSG is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FSG OCA].
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[[1fsg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxoplasma_gondii_rh Toxoplasma gondii rh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FSG OCA].
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==See Also==
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*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:11188695</ref><references group="xtra"/>
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<ref group="xtra">PMID:011188695</ref><references group="xtra"/><references/>
[[Category: Hypoxanthine phosphoribosyltransferase]]
[[Category: Hypoxanthine phosphoribosyltransferase]]
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[[Category: Toxoplasma gondii]]
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[[Category: Toxoplasma gondii rh]]
[[Category: Borhani, D W.]]
[[Category: Borhani, D W.]]
[[Category: Heroux, A.]]
[[Category: Heroux, A.]]
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[[Category: Glycosyltransferase]]
[[Category: Glycosyltransferase]]
[[Category: Purine salvage]]
[[Category: Purine salvage]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:29:28 2009''
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Revision as of 10:44, 16 April 2014

Template:STRUCTURE 1fsg

Contents

TOXOPLASMA GONDII HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH 9-DEAZAGUANINE, ALPHA-D-5-PHOSPHORIBOSYL-1-PYROPHOSPHATE (PRPP) AND TWO MG2+ IONS

Template:ABSTRACT PUBMED 11188695

Function

[HGXR_TOXGO] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to the N(9) of hypoxanthine, guanine or xanthine.[1]

About this Structure

1fsg is a 2 chain structure with sequence from Toxoplasma gondii rh. Full crystallographic information is available from OCA.

See Also

Reference

  • Heroux A, White EL, Ross LJ, Kuzin AP, Borhani DW. Substrate deformation in a hypoxanthine-guanine phosphoribosyltransferase ternary complex: the structural basis for catalysis. Structure. 2000 Dec 15;8(12):1309-18. PMID:11188695
  1. ↑ Heroux A, White EL, Ross LJ, Kuzin AP, Borhani DW. Substrate deformation in a hypoxanthine-guanine phosphoribosyltransferase ternary complex: the structural basis for catalysis. Structure. 2000 Dec 15;8(12):1309-18. PMID:11188695

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