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2g94
From Proteopedia
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===Crystal structure of beta-secretase bound to a potent and highly selective inhibitor.=== | ===Crystal structure of beta-secretase bound to a potent and highly selective inhibitor.=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2g94]] is a 4 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G94 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Beta secretase|Beta secretase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016620080</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
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[[Category: Beta secretase]] | [[Category: Beta secretase]] | ||
[[Category: Drug design]] | [[Category: Drug design]] | ||
| + | [[Category: Hydrolase]] | ||
[[Category: Memapsin]] | [[Category: Memapsin]] | ||
[[Category: Protease inhibitor]] | [[Category: Protease inhibitor]] | ||
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Revision as of 23:42, 25 July 2012
Contents |
Crystal structure of beta-secretase bound to a potent and highly selective inhibitor.
Template:ABSTRACT PUBMED 16620080
About this Structure
2g94 is a 4 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Ghosh AK, Kumaragurubaran N, Hong L, Lei H, Hussain KA, Liu CF, Devasamudram T, Weerasena V, Turner R, Koelsch G, Bilcer G, Tang J. Design, synthesis and X-ray structure of protein-ligand complexes: important insight into selectivity of memapsin 2 (beta-secretase) inhibitors. J Am Chem Soc. 2006 Apr 26;128(16):5310-1. PMID:16620080 doi:10.1021/ja058636j
Categories: Homo sapiens | Memapsin 2 | Ghosh, A. | Hong, L. | Tang, J. | Alzheimer's disease | Asp2 | Aspartic protease | Bace | Beta secretase | Drug design | Hydrolase | Memapsin | Protease inhibitor
