2g94

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[[Image:2g94.png|left|200px]]
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{{STRUCTURE_2g94| PDB=2g94 | SCENE= }}
{{STRUCTURE_2g94| PDB=2g94 | SCENE= }}
===Crystal structure of beta-secretase bound to a potent and highly selective inhibitor.===
===Crystal structure of beta-secretase bound to a potent and highly selective inhibitor.===
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{{ABSTRACT_PUBMED_16620080}}
{{ABSTRACT_PUBMED_16620080}}
==About this Structure==
==About this Structure==
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2G94 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G94 OCA].
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[[2g94]] is a 4 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G94 OCA].
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==See Also==
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*[[Beta secretase|Beta secretase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:16620080</ref><references group="xtra"/>
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<ref group="xtra">PMID:016620080</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
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[[Category: Beta secretase]]
[[Category: Beta secretase]]
[[Category: Drug design]]
[[Category: Drug design]]
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[[Category: Hydrolase]]
[[Category: Memapsin]]
[[Category: Memapsin]]
[[Category: Protease inhibitor]]
[[Category: Protease inhibitor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:58:52 2009''
 

Revision as of 23:42, 25 July 2012

Image:2g94.png

Template:STRUCTURE 2g94

Contents

Crystal structure of beta-secretase bound to a potent and highly selective inhibitor.

Template:ABSTRACT PUBMED 16620080

About this Structure

2g94 is a 4 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Ghosh AK, Kumaragurubaran N, Hong L, Lei H, Hussain KA, Liu CF, Devasamudram T, Weerasena V, Turner R, Koelsch G, Bilcer G, Tang J. Design, synthesis and X-ray structure of protein-ligand complexes: important insight into selectivity of memapsin 2 (beta-secretase) inhibitors. J Am Chem Soc. 2006 Apr 26;128(16):5310-1. PMID:16620080 doi:10.1021/ja058636j

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OCA

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