This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2c3k
From Proteopedia
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:2c3k.png|left|200px]] | [[Image:2c3k.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_2c3k", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_2c3k| PDB=2c3k | SCENE= }} | {{STRUCTURE_2c3k| PDB=2c3k | SCENE= }} | ||
===IDENTIFICATION OF A BURIED POCKET FOR POTENT AND SELECTIVE INHIBITION OF CHK1: PREDICTION AND VERIFICATION=== | ===IDENTIFICATION OF A BURIED POCKET FOR POTENT AND SELECTIVE INHIBITION OF CHK1: PREDICTION AND VERIFICATION=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_16289938}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 16289938 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_16289938}} | {{ABSTRACT_PUBMED_16289938}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2c3k]] is a 1 chain structure of [[Serine/threonine protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C3K OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Serine/threonine protein kinase|Serine/threonine protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016289938</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
| Line 44: | Line 35: | ||
[[Category: Oncology]] | [[Category: Oncology]] | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Serine/threonine-protein kinase]] | [[Category: Serine/threonine-protein kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
| - | [[Category: Ubl conjugation]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:43:14 2009'' | ||
Revision as of 00:42, 26 July 2012
Contents |
IDENTIFICATION OF A BURIED POCKET FOR POTENT AND SELECTIVE INHIBITION OF CHK1: PREDICTION AND VERIFICATION
Template:ABSTRACT PUBMED 16289938
About this Structure
2c3k is a 1 chain structure of Serine/threonine protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Foloppe N, Fisher LM, Francis G, Howes R, Kierstan P, Potter A. Identification of a buried pocket for potent and selective inhibition of Chk1: prediction and verification. Bioorg Med Chem. 2006 Mar 15;14(6):1792-804. Epub 2005 Nov 9. PMID:16289938 doi:10.1016/j.bmc.2005.10.022
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Fisher, L M. | Foloppe, N. | Francis, G. | Howes, R. | Kierstan, P. | Potter, A. | Atp-binding | Cell cycle | Dna damage | Dna repair | Drug design | Kinase | Molecular modeling | Molecular recognition | Nuclear protein | Nucleotide-binding | Oncology | Phosphorylation | Serine/threonine-protein kinase | Transferase
