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2gnj
From Proteopedia
(Difference between revisions)
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[[Image:2gnj.png|left|200px]] | [[Image:2gnj.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2gnj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GNJ OCA]. | |
==Reference== | ==Reference== | ||
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[[Category: Rho-kinase]] | [[Category: Rho-kinase]] | ||
[[Category: Surrogate]] | [[Category: Surrogate]] | ||
| - | + | [[Category: Transferase/transferase inhibitor complex]] | |
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Revision as of 20:53, 14 March 2011
PKA three fold mutant model of Rho-kinase with Y-27632
Template:ABSTRACT PUBMED 16699172
About this Structure
2gnj is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
Reference
- Bonn S, Herrero S, Breitenlechner CB, Erlbruch A, Lehmann W, Engh RA, Gassel M, Bossemeyer D. Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity. J Biol Chem. 2006 Aug 25;281(34):24818-30. Epub 2006 May 12. PMID:16699172 doi:10.1074/jbc.M512374200
- Breitenlechner C, Gassel M, Hidaka H, Kinzel V, Huber R, Engh RA, Bossemeyer D. Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity. Structure. 2003 Dec;11(12):1595-607. PMID:14656443
