1ld8

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[[Image:1ld8.png|left|200px]]
[[Image:1ld8.png|left|200px]]
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{{STRUCTURE_1ld8| PDB=1ld8 | SCENE= }}
{{STRUCTURE_1ld8| PDB=1ld8 | SCENE= }}
===Co-crystal structure of Human Farnesyltransferase with farnesyldiphosphate and inhibitor compound 49===
===Co-crystal structure of Human Farnesyltransferase with farnesyldiphosphate and inhibitor compound 49===
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{{ABSTRACT_PUBMED_12036349}}
{{ABSTRACT_PUBMED_12036349}}
==About this Structure==
==About this Structure==
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1LD8 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LD8 OCA].
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[[1ld8]] is a 2 chain structure of [[Farnesyltransferase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LD8 OCA].
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==See Also==
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*[[Farnesyltransferase|Farnesyltransferase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:12036349</ref><references group="xtra"/>
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<ref group="xtra">PMID:012036349</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Beese, L S.]]
[[Category: Beese, L S.]]
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[[Category: Pftase]]
[[Category: Pftase]]
[[Category: Ra]]
[[Category: Ra]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:53:26 2009''
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Revision as of 00:56, 26 July 2012

Image:1ld8.png

Template:STRUCTURE 1ld8

Contents

Co-crystal structure of Human Farnesyltransferase with farnesyldiphosphate and inhibitor compound 49

Template:ABSTRACT PUBMED 12036349

About this Structure

1ld8 is a 2 chain structure of Farnesyltransferase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Bell IM, Gallicchio SN, Abrams M, Beese LS, Beshore DC, Bhimnathwala H, Bogusky MJ, Buser CA, Culberson JC, Davide J, Ellis-Hutchings M, Fernandes C, Gibbs JB, Graham SL, Hamilton KA, Hartman GD, Heimbrook DC, Homnick CF, Huber HE, Huff JR, Kassahun K, Koblan KS, Kohl NE, Lobell RB, Lynch JJ Jr, Robinson R, Rodrigues AD, Taylor JS, Walsh ES, Williams TM, Zartman CB. 3-Aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency. J Med Chem. 2002 Jun 6;45(12):2388-409. PMID:12036349

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