2fak
From Proteopedia
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[[Image:2fak.png|left|200px]] | [[Image:2fak.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2fak]] is a 28 chain structure of [[Proteasome]] with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FAK OCA]. | |
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| + | ==See Also== | ||
| + | *[[Proteasome]] | ||
==Reference== | ==Reference== | ||
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[[Category: Potts, B C.]] | [[Category: Potts, B C.]] | ||
[[Category: Drug design]] | [[Category: Drug design]] | ||
| + | [[Category: Hydrolase]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Proteasome]] | [[Category: Proteasome]] | ||
[[Category: Ubiquitin]] | [[Category: Ubiquitin]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 22:10:40 2009'' | ||
Revision as of 21:16, 26 December 2010
Contents |
Crystal structure of Salinosporamide A in complex with the yeast 20S proteasome
Template:ABSTRACT PUBMED 16608349
About this Structure
2fak is a 28 chain structure of Proteasome with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
See Also
Reference
- Groll M, Huber R, Potts BC. Crystal structures of Salinosporamide A (NPI-0052) and B (NPI-0047) in complex with the 20S proteasome reveal important consequences of beta-lactone ring opening and a mechanism for irreversible binding. J Am Chem Soc. 2006 Apr 19;128(15):5136-41. PMID:16608349 doi:10.1021/ja058320b
