This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1y57
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:1y57.png|left|200px]] | [[Image:1y57.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_1y57", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_1y57| PDB=1y57 | SCENE= }} | {{STRUCTURE_1y57| PDB=1y57 | SCENE= }} | ||
===Structure of unphosphorylated c-Src in complex with an inhibitor=== | ===Structure of unphosphorylated c-Src in complex with an inhibitor=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_15939018}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 15939018 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_15939018}} | {{ABSTRACT_PUBMED_15939018}} | ||
| - | |||
| - | ==Disease== | ||
| - | Known disease associated with this structure: Colon cancer, advanced OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190090 190090]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1y57]] is a 1 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y57 OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]] | ||
| + | *[[SRC|SRC]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015939018</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
| Line 39: | Line 28: | ||
[[Category: Sh2]] | [[Category: Sh2]] | ||
[[Category: Sh3]] | [[Category: Sh3]] | ||
| - | + | [[Category: Transferase]] | |
| - | + | ||
Revision as of 02:34, 26 July 2012
Contents |
Structure of unphosphorylated c-Src in complex with an inhibitor
Template:ABSTRACT PUBMED 15939018
About this Structure
1y57 is a 1 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Cowan-Jacob SW, Fendrich G, Manley PW, Jahnke W, Fabbro D, Liebetanz J, Meyer T. The crystal structure of a c-Src complex in an active conformation suggests possible steps in c-Src activation. Structure. 2005 Jun;13(6):861-71. PMID:15939018 doi:10.1016/j.str.2005.03.012
Categories: Homo sapiens | Transferase | Cowan-Jacob, S W. | Fabbro, D. | Fendrich, G. | Jahnke, W. | Liebetanz, J. | Manley, P W. | Meyer, T. | Kinase structure | Sh2 | Sh3
