1t15
From Proteopedia
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[[Image:1t15.png|left|200px]] | [[Image:1t15.png|left|200px]] | ||
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{{STRUCTURE_1t15| PDB=1t15 | SCENE= }} | {{STRUCTURE_1t15| PDB=1t15 | SCENE= }} | ||
===Crystal Structure of the Brca1 BRCT Domains in Complex with the Phosphorylated Interacting Region from Bach1 Helicase=== | ===Crystal Structure of the Brca1 BRCT Domains in Complex with the Phosphorylated Interacting Region from Bach1 Helicase=== | ||
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{{ABSTRACT_PUBMED_15133502}} | {{ABSTRACT_PUBMED_15133502}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Breast cancer-1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Breast-ovarian cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Ovarian cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Papillary serous carcinoma of the peritoneum OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1t15]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T15 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015133502</ref><ref group="xtra">PMID:016544327</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Clapperton, J A.]] | [[Category: Clapperton, J A.]] | ||
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[[Category: Smerdon, S J.]] | [[Category: Smerdon, S J.]] | ||
[[Category: Yaffe, M B.]] | [[Category: Yaffe, M B.]] | ||
| + | [[Category: Antitumor protein]] | ||
[[Category: Protein-peptide complex]] | [[Category: Protein-peptide complex]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:00:51 2009'' | ||
Revision as of 13:41, 5 January 2013
Crystal Structure of the Brca1 BRCT Domains in Complex with the Phosphorylated Interacting Region from Bach1 Helicase
Template:ABSTRACT PUBMED 15133502
About this Structure
1t15 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Clapperton JA, Manke IA, Lowery DM, Ho T, Haire LF, Yaffe MB, Smerdon SJ. Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer. Nat Struct Mol Biol. 2004 Jun;11(6):512-8. Epub 2004 May 9. PMID:15133502 doi:10.1038/nsmb775
- Liu YJ, Cheng CS, Lai SM, Hsu MP, Chen CS, Lyu PC. Solution structure of the plant defensin VrD1 from mung bean and its possible role in insecticidal activity against bruchids. Proteins. 2006 Jun 1;63(4):777-86. PMID:16544327 doi:10.1002/prot.20962
