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1zxj
From Proteopedia
(New page: 200px<br /><applet load="1zxj" size="450" color="white" frame="true" align="right" spinBox="true" caption="1zxj, resolution 2.80Å" /> '''Crystal structure of...) |
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| - | [[Image:1zxj.gif|left|200px]]<br /><applet load="1zxj" size=" | + | [[Image:1zxj.gif|left|200px]]<br /><applet load="1zxj" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1zxj, resolution 2.80Å" /> | caption="1zxj, resolution 2.80Å" /> | ||
'''Crystal structure of the hypthetical Mycoplasma protein, MPN555'''<br /> | '''Crystal structure of the hypthetical Mycoplasma protein, MPN555'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The crystal structure of the hypothetical protein MPN555 from Mycoplasma | + | The crystal structure of the hypothetical protein MPN555 from Mycoplasma pneumoniae (gi|1673958) has been determined to a resolution of 2.8 Angstrom using anomalous diffraction data at the Se-peak wavelength. Structure determination revealed a mostly alpha-helical protein with a three-lobed shape. The three lobes or fingers delineate a central binding groove and additional grooves between lobes 1 and 3 and between lobes 2 and 3. For one of the molecules in the asymmetric unit, the central binding pocket was filled with a peptide from the uncleaved N-terminal affinity tag. The MPN555 structure has structural homology to two bacterial chaperone proteins: SurA and trigger factor from Escherichia coli. The structural data and the homology to other chaperone proteins suggests an involvement in protein folding as a molecular chaperone for MPN555. |
==About this Structure== | ==About this Structure== | ||
| - | 1ZXJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycoplasma_pneumoniae Mycoplasma pneumoniae]. Full crystallographic information is available from [http:// | + | 1ZXJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycoplasma_pneumoniae Mycoplasma pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZXJ OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Aono, S.]] | [[Category: Aono, S.]] | ||
| - | [[Category: BSGC, Berkeley | + | [[Category: BSGC, Berkeley Structural Genomics Center.]] |
[[Category: Kim, R.]] | [[Category: Kim, R.]] | ||
| - | [[Category: Kim, S | + | [[Category: Kim, S H.]] |
[[Category: Schulze-Gahmen, U.]] | [[Category: Schulze-Gahmen, U.]] | ||
[[Category: Shengfeng, C.]] | [[Category: Shengfeng, C.]] | ||
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[[Category: tri-lobal structure]] | [[Category: tri-lobal structure]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:20:05 2008'' |
Revision as of 14:20, 21 February 2008
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Crystal structure of the hypthetical Mycoplasma protein, MPN555
Overview
The crystal structure of the hypothetical protein MPN555 from Mycoplasma pneumoniae (gi|1673958) has been determined to a resolution of 2.8 Angstrom using anomalous diffraction data at the Se-peak wavelength. Structure determination revealed a mostly alpha-helical protein with a three-lobed shape. The three lobes or fingers delineate a central binding groove and additional grooves between lobes 1 and 3 and between lobes 2 and 3. For one of the molecules in the asymmetric unit, the central binding pocket was filled with a peptide from the uncleaved N-terminal affinity tag. The MPN555 structure has structural homology to two bacterial chaperone proteins: SurA and trigger factor from Escherichia coli. The structural data and the homology to other chaperone proteins suggests an involvement in protein folding as a molecular chaperone for MPN555.
About this Structure
1ZXJ is a Single protein structure of sequence from Mycoplasma pneumoniae. Full crystallographic information is available from OCA.
Reference
Structure of the hypothetical Mycoplasma protein MPN555 suggests a chaperone function., Schulze-Gahmen U, Aono S, Chen S, Yokota H, Kim R, Kim SH, Acta Crystallogr D Biol Crystallogr. 2005 Oct;61(Pt 10):1343-7. Epub 2005, Sep 28. PMID:16204885
Page seeded by OCA on Thu Feb 21 16:20:05 2008
Categories: Mycoplasma pneumoniae | Single protein | Aono, S. | BSGC, Berkeley Structural Genomics Center. | Kim, R. | Kim, S H. | Schulze-Gahmen, U. | Shengfeng, C. | Yokota, H. | Berkeley structural genomics center | Bsgc | Mostly alpha helical protein | Protein structure initiative | Psi | Structural genomics | Tri-lobal structure
