3cy2
From Proteopedia
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[[Image:3cy2.png|left|200px]] | [[Image:3cy2.png|left|200px]] | ||
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===Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a beta carboline ligand II=== | ===Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a beta carboline ligand II=== | ||
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_22136433}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 22136433 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_22136433}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3cy2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CY2 OCA]. | |
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022136433</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
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[[Category: Alternative initiation]] | [[Category: Alternative initiation]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
| - | [[Category: Cytoplasm]] | ||
[[Category: Host-virus interaction]] | [[Category: Host-virus interaction]] | ||
[[Category: Kinase]] | [[Category: Kinase]] | ||
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[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Pim1]] | [[Category: Pim1]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Proto-oncogene]] | [[Category: Proto-oncogene]] | ||
[[Category: Serine-threonine]] | [[Category: Serine-threonine]] | ||
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[[Category: Virion]] | [[Category: Virion]] | ||
[[Category: Virulence]] | [[Category: Virulence]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:30:25 2009'' | ||
Revision as of 09:57, 18 January 2012
Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a beta carboline ligand II
Template:ABSTRACT PUBMED 22136433
About this Structure
3cy2 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Huber K, Brault L, Fedorov O, Gasser C, Filippakopoulos P, Bullock AN, Fabbro D, Trappe J, Schwaller J, Knapp S, Bracher F. 7,8-Dichloro-1-oxo-beta-carbolines as a Versatile Scaffold for the Development of Potent and Selective Kinase Inhibitors with Unusual Binding Modes. J Med Chem. 2012 Jan 12;55(1):403-13. Epub 2012 Jan 3. PMID:22136433 doi:10.1021/jm201286z
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Arrowsmith, C H. | Bountra, C. | Bracher, F. | Bullock, A. | Delft, F von. | Edwards, A M. | Fedorov, O. | Filippakopoulos, P. | Huber, K. | Knapp, S. | Pike, A C.W. | SGC, Structural Genomics Consortium. | Alternative initiation | Atp-binding | Host-virus interaction | Kinase | Manganese | Membrane | Metal-binding | Nucleotide-binding | Nucleus | Oncogene | Phosphoprotein | Pim1 | Proto-oncogene | Serine-threonine | Serine/threonine-protein kinase | Sgc | Structural genomics consortium | Transferase | Viral immunoevasion | Virion | Virulence
