2r4b
From Proteopedia
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{{STRUCTURE_2r4b| PDB=2r4b | SCENE= }} | {{STRUCTURE_2r4b| PDB=2r4b | SCENE= }} | ||
===ErbB4 kinase domain complexed with a thienopyrimidine inhibitor=== | ===ErbB4 kinase domain complexed with a thienopyrimidine inhibitor=== | ||
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{{ABSTRACT_PUBMED_18287036}} | {{ABSTRACT_PUBMED_18287036}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2r4b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R4B OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018287036</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
[[Category: Shewchuk, L M.]] | [[Category: Shewchuk, L M.]] | ||
[[Category: Uehling, D E.]] | [[Category: Uehling, D E.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Erb]] | [[Category: Erb]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
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Revision as of 20:59, 7 January 2013
ErbB4 kinase domain complexed with a thienopyrimidine inhibitor
Template:ABSTRACT PUBMED 18287036
About this Structure
2r4b is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Wood ER, Shewchuk LM, Ellis B, Brignola P, Brashear RL, Caferro TR, Dickerson SH, Dickson HD, Donaldson KH, Gaul M, Griffin RJ, Hassell AM, Keith B, Mullin R, Petrov KG, Reno MJ, Rusnak DW, Tadepalli SM, Ulrich JC, Wagner CD, Vanderwall DE, Waterson AG, Williams JD, White WL, Uehling DE. 6-Ethynylthieno[3,2-d]- and 6-ethynylthieno[2,3-d]pyrimidin-4-anilines as tunable covalent modifiers of ErbB kinases. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2773-8. Epub 2008 Feb 19. PMID:18287036
