Template:STRUCTURE 1bzy

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{{Structure
{{Structure
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|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1bzy]], resolution 2.00&Aring; (<scene name='initialview01'>default scene</scene>)}}}
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|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1bzy]], [[Resolution|resolution]] 2.00&Aring; (<scene name='initialview01'>default scene</scene>)}}}
|LIGAND= <scene name='pdbligand=IMU:PHOSPHORIC+ACID+MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN-2-YLMETHYL]+ESTER'>IMU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>
|LIGAND= <scene name='pdbligand=IMU:PHOSPHORIC+ACID+MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN-2-YLMETHYL]+ESTER'>IMU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Hypoxanthine_phosphoribosyltransferase Hypoxanthine phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.8 2.4.2.8] </span>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Hypoxanthine_phosphoribosyltransferase Hypoxanthine phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.8 2.4.2.8] </span>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG0634 Hpt]</span>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bzy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bzy RCSB], [http://www.ebi.ac.uk/pdbsum/1bzy PDBsum]</span>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bzy OCA], [http://www.ebi.ac.uk/pdbsum/1bzy PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1bzy RCSB]</span>
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|FUNCTION={{GO|id=GO:0016757 | text = transferase activity, transferring glycosyl groups}}{{GO|id=GO:0004422 | text = hypoxanthine phosphoribosyltransferase activity}}{{GO|id=GO:0005515 | text = protein binding}}{{GO|id=GO:0042803 | text = protein homodimerization activity}}{{GO|id=GO:0016740 | text = transferase activity}}{{GO|id=GO:0000287 | text = magnesium ion binding}}{{GO|id=GO:0046872 | text = metal ion binding}}
|FUNCTION={{GO|id=GO:0016757 | text = transferase activity, transferring glycosyl groups}}{{GO|id=GO:0004422 | text = hypoxanthine phosphoribosyltransferase activity}}{{GO|id=GO:0005515 | text = protein binding}}{{GO|id=GO:0042803 | text = protein homodimerization activity}}{{GO|id=GO:0016740 | text = transferase activity}}{{GO|id=GO:0000287 | text = magnesium ion binding}}{{GO|id=GO:0046872 | text = metal ion binding}}
|PROCESS={{GO|id=GO:0006164 | text = purine nucleotide biosynthetic process}}{{GO|id=GO:0006166 | text = purine ribonucleoside salvage}}{{GO|id=GO:0009116 | text = nucleoside metabolic process}}{{GO|id=GO:0046100 | text = hypoxanthine metabolic process}}{{GO|id=GO:0051289 | text = protein homotetramerization}}{{GO|id=GO:0007610 | text = behavior}}{{GO|id=GO:0045964 | text = positive regulation of dopamine metabolic process}}
|PROCESS={{GO|id=GO:0006164 | text = purine nucleotide biosynthetic process}}{{GO|id=GO:0006166 | text = purine ribonucleoside salvage}}{{GO|id=GO:0009116 | text = nucleoside metabolic process}}{{GO|id=GO:0046100 | text = hypoxanthine metabolic process}}{{GO|id=GO:0051289 | text = protein homotetramerization}}{{GO|id=GO:0007610 | text = behavior}}{{GO|id=GO:0045964 | text = positive regulation of dopamine metabolic process}}
|COMPONENT={{GO|id=GO:0005737 | text = cytoplasm}}
|COMPONENT={{GO|id=GO:0005737 | text = cytoplasm}}
|SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1bzyA00 1Bzya00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1bzyB00 1Bzyb00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1bzyC00 1Bzyc00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1bzyD00 1Bzyd00]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR005904 Ipr005904], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002375 Ipr002375], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000836 Ipr000836]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00156 PF00156]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=34071 d1bzya_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=34072 d1bzyb_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=34073 d1bzyc_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=34074 d1bzyd_]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P00492 P00492]</span>
|SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1bzyA00 1Bzya00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1bzyB00 1Bzyb00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1bzyC00 1Bzyc00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1bzyD00 1Bzyd00]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR005904 Ipr005904], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002375 Ipr002375], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000836 Ipr000836]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00156 PF00156]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=34071 d1bzya_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=34072 d1bzyb_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=34073 d1bzyc_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=34074 d1bzyd_]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P00492 P00492]</span>
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|FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=HPRT1 HPRT1]</span>
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|uPDB=1BZY|CONSURF={{!}}-
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|CONSURF={{!}}-
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{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"

Current revision

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1bzy, resolution 2.00Å ()
Ligands: , ,
Activity: Hypoxanthine phosphoribosyltransferase, with EC number 2.4.2.8
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml


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