2a18
From Proteopedia
(New page: 200px<br /><applet load="2a18" size="450" color="white" frame="true" align="right" spinBox="true" caption="2a18, resolution 2.28Å" /> '''carboxysome shell pr...) |
|||
| Line 1: | Line 1: | ||
| - | [[Image:2a18.gif|left|200px]]<br /><applet load="2a18" size=" | + | [[Image:2a18.gif|left|200px]]<br /><applet load="2a18" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="2a18, resolution 2.28Å" /> | caption="2a18, resolution 2.28Å" /> | ||
'''carboxysome shell protein ccmK4, crystal form 2'''<br /> | '''carboxysome shell protein ccmK4, crystal form 2'''<br /> | ||
==Overview== | ==Overview== | ||
| - | Bacterial microcompartments are primitive organelles composed entirely of | + | Bacterial microcompartments are primitive organelles composed entirely of protein subunits. Genomic sequence databases reveal the widespread occurrence of microcompartments across diverse microbes. The prototypical bacterial microcompartment is the carboxysome, a protein shell for sequestering carbon fixation reactions. We report three-dimensional crystal structures of multiple carboxysome shell proteins, revealing a hexameric unit as the basic microcompartment building block and showing how these hexamers assemble to form flat facets of the polyhedral shell. The structures suggest how molecular transport across the shell may be controlled and how structural variations might govern the assembly and architecture of these subcellular compartments. |
==About this Structure== | ==About this Structure== | ||
| - | 2A18 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Synechocystis_sp. Synechocystis sp.] with NH4 as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http:// | + | 2A18 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Synechocystis_sp. Synechocystis sp.] with <scene name='pdbligand=NH4:'>NH4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A18 OCA]. |
==Reference== | ==Reference== | ||
| Line 14: | Line 14: | ||
[[Category: Synechocystis sp.]] | [[Category: Synechocystis sp.]] | ||
[[Category: Beeby, M.]] | [[Category: Beeby, M.]] | ||
| - | [[Category: Kerfeld, C | + | [[Category: Kerfeld, C A.]] |
| - | [[Category: Nguyen, C | + | [[Category: Nguyen, C V.]] |
[[Category: Phillips, M.]] | [[Category: Phillips, M.]] | ||
| - | [[Category: Sawaya, M | + | [[Category: Sawaya, M R.]] |
[[Category: Tanaka, S.]] | [[Category: Tanaka, S.]] | ||
| - | [[Category: Yeates, T | + | [[Category: Yeates, T O.]] |
[[Category: NH4]] | [[Category: NH4]] | ||
[[Category: cyclic hexamer; c6 point symmetry]] | [[Category: cyclic hexamer; c6 point symmetry]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:22:35 2008'' |
Revision as of 14:22, 21 February 2008
|
carboxysome shell protein ccmK4, crystal form 2
Overview
Bacterial microcompartments are primitive organelles composed entirely of protein subunits. Genomic sequence databases reveal the widespread occurrence of microcompartments across diverse microbes. The prototypical bacterial microcompartment is the carboxysome, a protein shell for sequestering carbon fixation reactions. We report three-dimensional crystal structures of multiple carboxysome shell proteins, revealing a hexameric unit as the basic microcompartment building block and showing how these hexamers assemble to form flat facets of the polyhedral shell. The structures suggest how molecular transport across the shell may be controlled and how structural variations might govern the assembly and architecture of these subcellular compartments.
About this Structure
2A18 is a Single protein structure of sequence from Synechocystis sp. with as ligand. Full crystallographic information is available from OCA.
Reference
Protein structures forming the shell of primitive bacterial organelles., Kerfeld CA, Sawaya MR, Tanaka S, Nguyen CV, Phillips M, Beeby M, Yeates TO, Science. 2005 Aug 5;309(5736):936-8. PMID:16081736
Page seeded by OCA on Thu Feb 21 16:22:35 2008
