2pl0
From Proteopedia
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{{STRUCTURE_2pl0| PDB=2pl0 | SCENE= }} | {{STRUCTURE_2pl0| PDB=2pl0 | SCENE= }} | ||
===LCK bound to imatinib=== | ===LCK bound to imatinib=== | ||
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{{ABSTRACT_PUBMED_17910071}} | {{ABSTRACT_PUBMED_17910071}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: SCID due to LCK deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=153390 153390]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2pl0]] is a 1 chain structure of [[Proto-oncogene tyrosine-protein kinase]] and [[Tyrosine kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PL0 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]] | ||
| + | *[[Tyrosine kinase|Tyrosine kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017910071</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific protein-tyrosine kinase]] | [[Category: Non-specific protein-tyrosine kinase]] | ||
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[[Category: Kinase phosphorylation]] | [[Category: Kinase phosphorylation]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 02:23:36 2009'' | ||
Revision as of 04:40, 26 July 2012
Contents |
LCK bound to imatinib
Template:ABSTRACT PUBMED 17910071
About this Structure
2pl0 is a 1 chain structure of Proto-oncogene tyrosine-protein kinase and Tyrosine kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Jacobs MD, Caron PR, Hare BJ. Classifying protein kinase structures guides use of ligand-selectivity profiles to predict inactive conformations: Structure of lck/imatinib complex. Proteins. 2007 Oct 1;70(4):1451-1460. PMID:17910071 doi:10.1002/prot.21633
