1t89

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[[Image:1t89.png|left|200px]]
 
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{{STRUCTURE_1t89| PDB=1t89 | SCENE= }}
{{STRUCTURE_1t89| PDB=1t89 | SCENE= }}
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===CRYSTAL STRUCTURE OF A HUMAN TYPE III FC GAMMA RECEPTOR IN COMPLEX WITH AN FC FRAGMENT OF IGG1 (HEXAGONAL)===
===CRYSTAL STRUCTURE OF A HUMAN TYPE III FC GAMMA RECEPTOR IN COMPLEX WITH AN FC FRAGMENT OF IGG1 (HEXAGONAL)===
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{{ABSTRACT_PUBMED_11297532}}
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==Function==
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[[http://www.uniprot.org/uniprot/FCG3B_HUMAN FCG3B_HUMAN]] Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
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{{ABSTRACT_PUBMED_11297532}}
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==About this Structure==
==About this Structure==
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1T89 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1iix 1iix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T89 OCA].
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[[1t89]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1iix 1iix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T89 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:11297532</ref><references group="xtra"/>
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<ref group="xtra">PMID:011297532</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Fridman, W H.]]
[[Category: Fridman, W H.]]
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[[Category: Fcgriii]]
[[Category: Fcgriii]]
[[Category: Igg1]]
[[Category: Igg1]]
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[[Category: Immune system]]
[[Category: Immunoglobulin]]
[[Category: Immunoglobulin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:04:56 2009''
 

Revision as of 22:35, 24 March 2013

Template:STRUCTURE 1t89

Contents

CRYSTAL STRUCTURE OF A HUMAN TYPE III FC GAMMA RECEPTOR IN COMPLEX WITH AN FC FRAGMENT OF IGG1 (HEXAGONAL)

Template:ABSTRACT PUBMED 11297532

Function

[FCG3B_HUMAN] Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.

About this Structure

1t89 is a 3 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1iix. Full crystallographic information is available from OCA.

Reference

  • Radaev S, Motyka S, Fridman WH, Sautes-Fridman C, Sun PD. The structure of a human type III Fcgamma receptor in complex with Fc. J Biol Chem. 2001 May 11;276(19):16469-77. Epub 2001 Jan 31. PMID:11297532 doi:10.1074/jbc.M100350200

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OCA

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