3caj
From Proteopedia
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[[Image:3caj.png|left|200px]] | [[Image:3caj.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3caj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CAJ OCA]. | |
==Reference== | ==Reference== | ||
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[[Category: Protein-inhibitor complex]] | [[Category: Protein-inhibitor complex]] | ||
[[Category: Zinc]] | [[Category: Zinc]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:27:14 2009'' | ||
Revision as of 18:41, 14 March 2011
Crystal structure of the human carbonic anhydrase II in complex with ethoxzolamide
Template:ABSTRACT PUBMED 18359629
About this Structure
3caj is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Di Fiore A, Pedone C, Antel J, Waldeck H, Witte A, Wurl M, Scozzafava A, Supuran CT, De Simone G. Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitors. Bioorg Med Chem Lett. 2008 Apr 15;18(8):2669-74. Epub 2008 Mar 18. PMID:18359629 doi:10.1016/j.bmcl.2008.03.023
- Smith GM, Alexander RS, Christianson DW, McKeever BM, Ponticello GS, Springer JP, Randall WC, Baldwin JJ, Habecker CN. Positions of His-64 and a bound water in human carbonic anhydrase II upon binding three structurally related inhibitors. Protein Sci. 1994 Jan;3(1):118-25. PMID:8142888
- Stams T, Chen Y, Boriack-Sjodin PA, Hurt JD, Liao J, May JA, Dean T, Laipis P, Silverman DN, Christianson DW. Structures of murine carbonic anhydrase IV and human carbonic anhydrase II complexed with brinzolamide: molecular basis of isozyme-drug discrimination. Protein Sci. 1998 Mar;7(3):556-63. PMID:9541386 doi:10.1002/pro.5560070303
