2oo4
From Proteopedia
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[[Image:2oo4.png|left|200px]] | [[Image:2oo4.png|left|200px]] | ||
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{{STRUCTURE_2oo4| PDB=2oo4 | SCENE= }} | {{STRUCTURE_2oo4| PDB=2oo4 | SCENE= }} | ||
===Structure of LNR-HD (Negative Regulatory Region) from human Notch 2=== | ===Structure of LNR-HD (Negative Regulatory Region) from human Notch 2=== | ||
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{{ABSTRACT_PUBMED_17401372}} | {{ABSTRACT_PUBMED_17401372}} | ||
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- | ==Disease== | ||
- | Known disease associated with this structure: Alagille syndrome 2 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600275 600275]] | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[2oo4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OO4 OCA]. | |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017401372</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Aster, J C.]] | [[Category: Aster, J C.]] | ||
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[[Category: Vardar-Ulu, D.]] | [[Category: Vardar-Ulu, D.]] | ||
[[Category: Alpha-beta-sandwich]] | [[Category: Alpha-beta-sandwich]] | ||
+ | [[Category: Cell cycle]] | ||
[[Category: Cysteine-rich]] | [[Category: Cysteine-rich]] | ||
[[Category: Hd domain]] | [[Category: Hd domain]] | ||
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[[Category: Lnr]] | [[Category: Lnr]] | ||
[[Category: Sea domain]] | [[Category: Sea domain]] | ||
- | + | [[Category: Signaling protein]] | |
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Revision as of 10:33, 7 January 2013
Structure of LNR-HD (Negative Regulatory Region) from human Notch 2
Template:ABSTRACT PUBMED 17401372
About this Structure
2oo4 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Gordon WR, Vardar-Ulu D, Histen G, Sanchez-Irizarry C, Aster JC, Blacklow SC. Structural basis for autoinhibition of Notch. Nat Struct Mol Biol. 2007 Apr;14(4):295-300. Epub 2007 Apr 1. PMID:17401372 doi:10.1038/nsmb1227