2zn7
From Proteopedia
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{{STRUCTURE_2zn7| PDB=2zn7 | SCENE= }} | {{STRUCTURE_2zn7| PDB=2zn7 | SCENE= }} | ||
===CRYSTAL STRUCTURES OF PTP1B-Inhibitor Complexes=== | ===CRYSTAL STRUCTURES OF PTP1B-Inhibitor Complexes=== | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Insulin resistance, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176885 176885]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2zn7]] is a 1 chain structure of [[Proten tyrosine phosphatase]] and [[Tyrosine phosphatase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZN7 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Proten tyrosine phosphatase|Proten tyrosine phosphatase]] | ||
| + | *[[Tyrosine phosphatase|Tyrosine phosphatase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018798205</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Protein-tyrosine-phosphatase]] | [[Category: Protein-tyrosine-phosphatase]] | ||
[[Category: Wu, J.]] | [[Category: Wu, J.]] | ||
[[Category: Xu, W.]] | [[Category: Xu, W.]] | ||
| - | [[Category: Acetylation]] | ||
[[Category: Endoplasmic reticulum]] | [[Category: Endoplasmic reticulum]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
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[[Category: Oxidation]] | [[Category: Oxidation]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protein phosphatase]] | [[Category: Protein phosphatase]] | ||
[[Category: Protein-inhibitor complex]] | [[Category: Protein-inhibitor complex]] | ||
[[Category: Ptp1b]] | [[Category: Ptp1b]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:48:38 2009'' | ||
Revision as of 07:12, 26 July 2012
Contents |
CRYSTAL STRUCTURES OF PTP1B-Inhibitor Complexes
About this Structure
2zn7 is a 1 chain structure of Proten tyrosine phosphatase and Tyrosine phosphatase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Wan ZK, Lee J, Hotchandani R, Moretto A, Binnun E, Wilson DP, Kirincich SJ, Follows BC, Ipek M, Xu W, Joseph-McCarthy D, Zhang YL, Tam M, Erbe DV, Tobin JF, Li W, Tam SY, Mansour TS, Wu J. Structure-based optimization of protein tyrosine phosphatase-1 B inhibitors: capturing interactions with arginine 24. ChemMedChem. 2008 Oct;3(10):1525-9. PMID:18798205 doi:10.1002/cmdc.200800188
