2r7g
From Proteopedia
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===Structure of the retinoblastoma protein pocket domain in complex with adenovirus E1A CR1 domain=== | ===Structure of the retinoblastoma protein pocket domain in complex with adenovirus E1A CR1 domain=== | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Bladder cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]], Osteosarcoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]], Pinealoma with bilateral retinoblastoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]], Retinoblastoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2r7g]] is a 5 chain structure of [[Retinoblastoma protein]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_adenovirus_5 Human adenovirus 5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R7G OCA]. | |
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| + | ==See Also== | ||
| + | *[[Retinoblastoma protein|Retinoblastoma protein]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017974914</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Human adenovirus 5]] | [[Category: Human adenovirus 5]] | ||
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[[Category: Retinoblastoma protein]] | [[Category: Retinoblastoma protein]] | ||
[[Category: Transcription repressor]] | [[Category: Transcription repressor]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:56:07 2009'' | ||
Revision as of 07:22, 26 July 2012
Contents |
Structure of the retinoblastoma protein pocket domain in complex with adenovirus E1A CR1 domain
Template:ABSTRACT PUBMED 17974914
About this Structure
2r7g is a 5 chain structure of Retinoblastoma protein with sequence from Homo sapiens and Human adenovirus 5. Full crystallographic information is available from OCA.
See Also
Reference
- Liu X, Marmorstein R. Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor. Genes Dev. 2007 Nov 1;21(21):2711-6. PMID:17974914 doi:21/21/2711
