1ex8
From Proteopedia
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{{STRUCTURE_1ex8| PDB=1ex8 | SCENE= }} | {{STRUCTURE_1ex8| PDB=1ex8 | SCENE= }} | ||
===CRYSTAL STRUCTURE OF 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE COMPLEXED WITH HP4A, THE TWO-SUBSTRATE-MIMICKING INHIBITOR=== | ===CRYSTAL STRUCTURE OF 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE COMPLEXED WITH HP4A, THE TWO-SUBSTRATE-MIMICKING INHIBITOR=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1ex8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EX8 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:011311059</ref><references group="xtra"/> |
[[Category: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase]] | [[Category: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
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[[Category: Active-site architecture]] | [[Category: Active-site architecture]] | ||
[[Category: Antimicrobial agent]] | [[Category: Antimicrobial agent]] | ||
| - | [[Category: Atp]] | ||
[[Category: Bisubstrate-mimicking inhibitor]] | [[Category: Bisubstrate-mimicking inhibitor]] | ||
[[Category: Drug design]] | [[Category: Drug design]] | ||
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[[Category: Pyrophosphoryl transfer]] | [[Category: Pyrophosphoryl transfer]] | ||
[[Category: Substrate specificity]] | [[Category: Substrate specificity]] | ||
| - | [[Category: | + | [[Category: Transferase]] |
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Revision as of 07:28, 14 November 2012
CRYSTAL STRUCTURE OF 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE COMPLEXED WITH HP4A, THE TWO-SUBSTRATE-MIMICKING INHIBITOR
About this Structure
1ex8 is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
- Shi G, Blaszczyk J, Ji X, Yan H. Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: synthesis and biochemical and crystallographic studies. J Med Chem. 2001 Apr 26;44(9):1364-71. PMID:11311059
Categories: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase | Escherichia coli | Blaszczyk, J. | Ji, X. | Active-site architecture | Antimicrobial agent | Bisubstrate-mimicking inhibitor | Drug design | Folate | Hppk | Pterin | Pyrophosphokinase | Pyrophosphoryl transfer | Substrate specificity | Transferase
