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1wq1
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_1wq1| PDB=1wq1 | SCENE= }} | {{STRUCTURE_1wq1| PDB=1wq1 | SCENE= }} | ||
===RAS-RASGAP COMPLEX=== | ===RAS-RASGAP COMPLEX=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1wq1]] is a 2 chain structure of [[GTPase HRas]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The April 2012 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Ras Protein'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2012_4 10.2210/rcsb_pdb/mom_2012_4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WQ1 OCA]. | |
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| + | ==See Also== | ||
| + | *[[GTPase HRas|GTPase HRas]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:009219684</ref><ref group="xtra">PMID:010899318</ref><ref group="xtra">PMID:015906320</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| + | [[Category: RCSB PDB Molecule of the Month]] | ||
| + | [[Category: Ras Protein]] | ||
[[Category: Ahmadian, M R.]] | [[Category: Ahmadian, M R.]] | ||
[[Category: Kabsch, W.]] | [[Category: Kabsch, W.]] | ||
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[[Category: Signal transduction]] | [[Category: Signal transduction]] | ||
[[Category: Transition state]] | [[Category: Transition state]] | ||
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Revision as of 07:57, 26 July 2012
Contents |
RAS-RASGAP COMPLEX
Template:ABSTRACT PUBMED 9219684
About this Structure
1wq1 is a 2 chain structure of GTPase HRas with sequence from Homo sapiens. The April 2012 RCSB PDB Molecule of the Month feature on Ras Protein by David Goodsell is 10.2210/rcsb_pdb/mom_2012_4. Full crystallographic information is available from OCA.
See Also
Reference
- Scheffzek K, Ahmadian MR, Kabsch W, Wiesmuller L, Lautwein A, Schmitz F, Wittinghofer A. The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants. Science. 1997 Jul 18;277(5324):333-8. PMID:9219684
- Souchet M, Poupon A, Callebaut I, Leger I, Mornon J, Bril A, Calmels TP. Functional specificity conferred by the unique plasticity of fully alpha-helical Ras and Rho GAPs. FEBS Lett. 2000 Jul 14;477(1-2):99-105. PMID:10899318
- Grigorenko BL, Nemukhin AV, Topol IA, Cachau RE, Burt SK. QM/MM modeling the Ras-GAP catalyzed hydrolysis of guanosine triphosphate. Proteins. 2005 Aug 15;60(3):495-503. PMID:15906320 doi:10.1002/prot.20472
