This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1rtl
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:1rtl.png|left|200px]] | [[Image:1rtl.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_1rtl", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_1rtl| PDB=1rtl | SCENE= }} | {{STRUCTURE_1rtl| PDB=1rtl | SCENE= }} | ||
===CRYSTAL STRUCTURE OF HCV NS3 PROTEASE DOMAIN: NS4A PEPTIDE COMPLEX WITH COVALENTLY BOUND PYRROLIDINE-5,5-TRANSLACTAM INHIBITOR=== | ===CRYSTAL STRUCTURE OF HCV NS3 PROTEASE DOMAIN: NS4A PEPTIDE COMPLEX WITH COVALENTLY BOUND PYRROLIDINE-5,5-TRANSLACTAM INHIBITOR=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_14627400}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 14627400 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_14627400}} | {{ABSTRACT_PUBMED_14627400}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1rtl]] is a 4 chain structure of [[Helicase]] with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RTL OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Helicase|Helicase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:014627400</ref><references group="xtra"/> |
[[Category: Hepatitis c virus]] | [[Category: Hepatitis c virus]] | ||
[[Category: Skarzynski, T.]] | [[Category: Skarzynski, T.]] | ||
| Line 34: | Line 25: | ||
[[Category: Translactam]] | [[Category: Translactam]] | ||
[[Category: Viral protein]] | [[Category: Viral protein]] | ||
| - | + | [[Category: Viral protein complex]] | |
| - | + | ||
Revision as of 08:11, 26 July 2012
Contents |
CRYSTAL STRUCTURE OF HCV NS3 PROTEASE DOMAIN: NS4A PEPTIDE COMPLEX WITH COVALENTLY BOUND PYRROLIDINE-5,5-TRANSLACTAM INHIBITOR
Template:ABSTRACT PUBMED 14627400
About this Structure
1rtl is a 4 chain structure of Helicase with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
See Also
Reference
- Slater MJ, Amphlett EM, Andrews DM, Bamborough P, Carey SJ, Johnson MR, Jones PS, Mills G, Parry NR, Somers DO, Stewart AJ, Skarzynski T. Pyrrolidine-5,5-trans-lactams. 4. Incorporation of a P3/P4 urea leads to potent intracellular inhibitors of hepatitis C virus NS3/4A protease. Org Lett. 2003 Nov 27;5(24):4627-30. PMID:14627400 doi:10.1021/ol035826v
