1b72

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[[Image:1b72.png|left|200px]]
[[Image:1b72.png|left|200px]]
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{{STRUCTURE_1b72| PDB=1b72 | SCENE= }}
{{STRUCTURE_1b72| PDB=1b72 | SCENE= }}
===PBX1, HOMEOBOX PROTEIN HOX-B1/DNA TERNARY COMPLEX===
===PBX1, HOMEOBOX PROTEIN HOX-B1/DNA TERNARY COMPLEX===
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{{ABSTRACT_PUBMED_10052460}}
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==Disease==
 
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Known disease associated with this structure: Leukemia, acute pre-B-cell OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176310 176310]]
 
==About this Structure==
==About this Structure==
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1B72 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B72 OCA].
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[[1b72]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B72 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:10052460</ref><references group="xtra"/>
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<ref group="xtra">PMID:010052460</ref><ref group="xtra">PMID:015048824</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Batchelor, A H.]]
[[Category: Batchelor, A H.]]
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[[Category: Dna-binding protein]]
[[Category: Dna-binding protein]]
[[Category: Homeodomain]]
[[Category: Homeodomain]]
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[[Category: Protein-dna complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 06:28:17 2009''
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Revision as of 14:30, 21 October 2012

Template:STRUCTURE 1b72

PBX1, HOMEOBOX PROTEIN HOX-B1/DNA TERNARY COMPLEX

Template:ABSTRACT PUBMED 10052460

About this Structure

1b72 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Piper DE, Batchelor AH, Chang CP, Cleary ML, Wolberger C. Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation. Cell. 1999 Feb 19;96(4):587-97. PMID:10052460
  • Hicks JM, Hsu VL. The extended left-handed helix: a simple nucleic acid-binding motif. Proteins. 2004 May 1;55(2):330-8. PMID:15048824 doi:10.1002/prot.10630

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