1eby
From Proteopedia
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[[Image:1eby.png|left|200px]] | [[Image:1eby.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1eby]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EBY OCA]. | |
==Reference== | ==Reference== | ||
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[[Category: Unge, T.]] | [[Category: Unge, T.]] | ||
[[Category: Dimer]] | [[Category: Dimer]] | ||
| + | [[Category: Hydrolase/hydrolase inhibitor complex]] | ||
[[Category: Protein-inhibitor complex]] | [[Category: Protein-inhibitor complex]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 06:45:46 2009'' | ||
Revision as of 00:37, 15 March 2011
HIV-1 protease in complex with the inhibitor BEA369
Template:ABSTRACT PUBMED 12694187
About this Structure
1eby is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
- Andersson HO, Fridborg K, Lowgren S, Alterman M, Muhlman A, Bjorsne M, Garg N, Kvarnstrom I, Schaal W, Classon B, Karlen A, Danielsson UH, Ahlsen G, Nillroth U, Vrang L, Oberg B, Samuelsson B, Hallberg A, Unge T. Optimization of P1-P3 groups in symmetric and asymmetric HIV-1 protease inhibitors. Eur J Biochem. 2003 Apr;270(8):1746-58. PMID:12694187
- Lindberg J, Pyring D, Lowgren S, Rosenquist A, Zuccarello G, Kvarnstrom I, Zhang H, Vrang L, Classon B, Hallberg A, Samuelsson B, Unge T. Symmetric fluoro-substituted diol-based HIV protease inhibitors. Ortho-fluorinated and meta-fluorinated P1/P1'-benzyloxy side groups significantly improve the antiviral activity and preserve binding efficacy. Eur J Biochem. 2004 Nov;271(22):4594-602. PMID:15560801 doi:10.1111/j.1432-1033.2004.04431.x
