2h07
From Proteopedia
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[[Image:2h07.png|left|200px]] | [[Image:2h07.png|left|200px]] | ||
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{{STRUCTURE_2h07| PDB=2h07 | SCENE= }} | {{STRUCTURE_2h07| PDB=2h07 | SCENE= }} | ||
===crystal structure of human phosphoribosyl pyrophosphate synthetase 1 mutant S132A=== | ===crystal structure of human phosphoribosyl pyrophosphate synthetase 1 mutant S132A=== | ||
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{{ABSTRACT_PUBMED_16939420}} | {{ABSTRACT_PUBMED_16939420}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Arts syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=311850 311850]], Charcot-Marie-Tooth disease, X-linked recessive, 5 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=311850 311850]], Gout, PRPS-related OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=311850 311850]], Phosphoribosylpyrophosphate synthetase superactivity OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=311850 311850]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2h07]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H07 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016939420</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Ribose-phosphate diphosphokinase]] | [[Category: Ribose-phosphate diphosphokinase]] | ||
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[[Category: Prpp synthetase 1]] | [[Category: Prpp synthetase 1]] | ||
[[Category: Prs1]] | [[Category: Prs1]] | ||
| - | + | [[Category: Transferase]] | |
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Revision as of 12:47, 7 January 2013
crystal structure of human phosphoribosyl pyrophosphate synthetase 1 mutant S132A
Template:ABSTRACT PUBMED 16939420
About this Structure
2h07 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Li S, Lu Y, Peng B, Ding J. Crystal structure of human phosphoribosylpyrophosphate synthetase 1 reveals a novel allosteric site. Biochem J. 2007 Jan 1;401(1):39-47. PMID:16939420 doi:10.1042/BJ20061066
