1t2u
From Proteopedia
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[[Image:1t2u.png|left|200px]] | [[Image:1t2u.png|left|200px]] | ||
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{{STRUCTURE_1t2u| PDB=1t2u | SCENE= }} | {{STRUCTURE_1t2u| PDB=1t2u | SCENE= }} | ||
===Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1: structure of BRCA1 missense variant V1809F=== | ===Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1: structure of BRCA1 missense variant V1809F=== | ||
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{{ABSTRACT_PUBMED_15133503}} | {{ABSTRACT_PUBMED_15133503}} | ||
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- | ==Disease== | ||
- | Known disease associated with this structure: Breast cancer-1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Breast-ovarian cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Ovarian cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Papillary serous carcinoma of the peritoneum OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]] | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[1t2u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T2U OCA]. | |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015133503</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Duong, D D.]] | [[Category: Duong, D D.]] | ||
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[[Category: Lee, M S.]] | [[Category: Lee, M S.]] | ||
[[Category: Williams, R S.]] | [[Category: Williams, R S.]] | ||
+ | [[Category: Antitumor protein]] | ||
[[Category: Brca1]] | [[Category: Brca1]] | ||
[[Category: Brct]] | [[Category: Brct]] | ||
[[Category: Missense mutation]] | [[Category: Missense mutation]] | ||
[[Category: Phospho-peptide]] | [[Category: Phospho-peptide]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 07:10:29 2009'' |
Revision as of 11:16, 5 January 2013
Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1: structure of BRCA1 missense variant V1809F
Template:ABSTRACT PUBMED 15133503
About this Structure
1t2u is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Williams RS, Lee MS, Hau DD, Glover JN. Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1. Nat Struct Mol Biol. 2004 Jun;11(6):519-25. Epub 2004 May 9. PMID:15133503 doi:http://dx.doi.org/10.1038/nsmb776