2gs6

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==About this Structure==
==About this Structure==
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2GS6 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GS6 OCA].
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[[2gs6]] is a 2 chain structure of [[Epidermal Growth Factor Receptor]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The June 2010 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Epidermal Growth Factor Receptor'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2010_6 10.2210/rcsb_pdb/mom_2010_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GS6 OCA].
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==See Also==
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*[[Epidermal Growth Factor Receptor]]
==Reference==
==Reference==
<ref group="xtra">PMID:16777603</ref><references group="xtra"/>
<ref group="xtra">PMID:16777603</ref><references group="xtra"/>
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[[Category: Epidermal Growth Factor Receptor]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: RCSB PDB Molecule of the Month]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Cole, P A.]]
[[Category: Cole, P A.]]
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[[Category: Shen, K.]]
[[Category: Shen, K.]]
[[Category: Zhang, X.]]
[[Category: Zhang, X.]]
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[[Category: Active]]
[[Category: Atp-analog peptide conjugate]]
[[Category: Atp-analog peptide conjugate]]
[[Category: Egfr]]
[[Category: Egfr]]
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[[Category: Kinase,active]]
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[[Category: Kinase]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 07:46:20 2009''
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Revision as of 00:46, 27 December 2010

Template:STRUCTURE 2gs6

Contents

Crystal Structure of the active EGFR kinase domain in complex with an ATP analog-peptide conjugate

Template:ABSTRACT PUBMED 16777603

About this Structure

2gs6 is a 2 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. The June 2010 RCSB PDB Molecule of the Month feature on Epidermal Growth Factor Receptor by David Goodsell is 10.2210/rcsb_pdb/mom_2010_6. Full crystallographic information is available from OCA.

See Also

Reference

  • Zhang X, Gureasko J, Shen K, Cole PA, Kuriyan J. An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor. Cell. 2006 Jun 16;125(6):1137-49. PMID:16777603 doi:10.1016/j.cell.2006.05.013

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