2bqv
From Proteopedia
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{{STRUCTURE_2bqv| PDB=2bqv | SCENE= }} | {{STRUCTURE_2bqv| PDB=2bqv | SCENE= }} | ||
===HIV-1 PROTEASE IN COMPLEX WITH INHIBITOR AHA455=== | ===HIV-1 PROTEASE IN COMPLEX WITH INHIBITOR AHA455=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2bqv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BQV OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016335934</ref><ref group="xtra">PMID:018215014</ref><references group="xtra"/> |
[[Category: HIV-1 retropepsin]] | [[Category: HIV-1 retropepsin]] | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
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[[Category: Hiv-1 protease]] | [[Category: Hiv-1 protease]] | ||
[[Category: Hydrolase complex]] | [[Category: Hydrolase complex]] | ||
| + | [[Category: Hydrolase-inhibitor complex]] | ||
| + | [[Category: Hydrolase/inhibitor]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
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Revision as of 09:57, 6 January 2013
HIV-1 PROTEASE IN COMPLEX WITH INHIBITOR AHA455
Template:ABSTRACT PUBMED 16335934
About this Structure
2bqv is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
- Ekegren JK, Unge T, Safa MZ, Wallberg H, Samuelsson B, Hallberg A. A new class of HIV-1 protease inhibitors containing a tertiary alcohol in the transition-state mimicking scaffold. J Med Chem. 2005 Dec 15;48(25):8098-102. PMID:16335934 doi:10.1021/jm050790t
- Wu X, Ohrngren P, Ekegren JK, Unge J, Unge T, Wallberg H, Samuelsson B, Hallberg A, Larhed M. Two-carbon-elongated HIV-1 protease inhibitors with a tertiary-alcohol-containing transition-state mimic. J Med Chem. 2008 Feb 28;51(4):1053-7. Epub 2008 Jan 24. PMID:18215014 doi:10.1021/jm070680h
