1kw0
From Proteopedia
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===Catalytic Domain of Human Phenylalanine Hydroxylase (Fe(II)) in Complex with Tetrahydrobiopterin and Thienylalanine=== | ===Catalytic Domain of Human Phenylalanine Hydroxylase (Fe(II)) in Complex with Tetrahydrobiopterin and Thienylalanine=== | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Phenylketonuria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=612349 612349]], Hyperphenylalaninemia, mild OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=612349 612349]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1kw0]] is a 1 chain structure of [[Phenylalanine hydroxylase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KW0 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Phenylalanine hydroxylase|Phenylalanine hydroxylase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:012126628</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Phenylalanine 4-monooxygenase]] | [[Category: Phenylalanine 4-monooxygenase]] | ||
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[[Category: Basket-arrangement 13 alpha-helices and 6 beta-strand]] | [[Category: Basket-arrangement 13 alpha-helices and 6 beta-strand]] | ||
[[Category: Ferrous iron]] | [[Category: Ferrous iron]] | ||
| - | + | [[Category: Oxidoreductase]] | |
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Revision as of 10:50, 26 July 2012
Contents |
Catalytic Domain of Human Phenylalanine Hydroxylase (Fe(II)) in Complex with Tetrahydrobiopterin and Thienylalanine
Template:ABSTRACT PUBMED 12126628
About this Structure
1kw0 is a 1 chain structure of Phenylalanine hydroxylase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Andersen OA, Flatmark T, Hough E. Crystal structure of the ternary complex of the catalytic domain of human phenylalanine hydroxylase with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine, and its implications for the mechanism of catalysis and substrate activation. J Mol Biol. 2002 Jul 26;320(5):1095-108. PMID:12126628
