2b6g
From Proteopedia
(New page: 200px<br /><applet load="2b6g" size="450" color="white" frame="true" align="right" spinBox="true" caption="2b6g" /> '''RNA recognition by the Vts1 SAM domain'''<br...) |
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| - | [[Image:2b6g.gif|left|200px]]<br /><applet load="2b6g" size=" | + | [[Image:2b6g.gif|left|200px]]<br /><applet load="2b6g" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="2b6g" /> | caption="2b6g" /> | ||
'''RNA recognition by the Vts1 SAM domain'''<br /> | '''RNA recognition by the Vts1 SAM domain'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The putative yeast post-transcriptional regulator Vts1p and its related | + | The putative yeast post-transcriptional regulator Vts1p and its related protein Smaug, from Drosophila melanogaster, each use a sterile alpha motif (SAM) domain to bind an RNA hairpin termed the Smaug recognition element (SRE). Here, we present the NMR structures of the Vts1p-SRE complex and the free SRE. Structural highlights include the direct recognition of a guanine base and the formation or stabilization of a base pair in the SRE loop. |
==About this Structure== | ==About this Structure== | ||
| - | 2B6G is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http:// | + | 2B6G is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B6G OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Donaldson, L | + | [[Category: Donaldson, L W.]] |
| - | [[Category: Johnson, P | + | [[Category: Johnson, P E.]] |
[[Category: alpha-helix]] | [[Category: alpha-helix]] | ||
[[Category: hairpin]] | [[Category: hairpin]] | ||
[[Category: pentaloop]] | [[Category: pentaloop]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:34:39 2008'' |
Revision as of 14:34, 21 February 2008
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RNA recognition by the Vts1 SAM domain
Overview
The putative yeast post-transcriptional regulator Vts1p and its related protein Smaug, from Drosophila melanogaster, each use a sterile alpha motif (SAM) domain to bind an RNA hairpin termed the Smaug recognition element (SRE). Here, we present the NMR structures of the Vts1p-SRE complex and the free SRE. Structural highlights include the direct recognition of a guanine base and the formation or stabilization of a base pair in the SRE loop.
About this Structure
2B6G is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
Reference
RNA recognition by the Vts1p SAM domain., Johnson PE, Donaldson LW, Nat Struct Mol Biol. 2006 Feb;13(2):177-8. Epub 2006 Jan 22. PMID:16429155
Page seeded by OCA on Thu Feb 21 16:34:39 2008
