2px6
From Proteopedia
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[[Image:2px6.png|left|200px]] | [[Image:2px6.png|left|200px]] | ||
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{{STRUCTURE_2px6| PDB=2px6 | SCENE= }} | {{STRUCTURE_2px6| PDB=2px6 | SCENE= }} | ||
===Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat=== | ===Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat=== | ||
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{{ABSTRACT_PUBMED_17618296}} | {{ABSTRACT_PUBMED_17618296}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Autoimmune lymphoproliferative syndrome, type IA OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=134637 134637]], Squamous cell carcinoma, burn scar-related, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=134637 134637]], Autoimmune lymphoproliferative syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=134637 134637]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2px6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PX6 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017618296</ref><references group="xtra"/> |
[[Category: Fatty-acid synthase]] | [[Category: Fatty-acid synthase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Tetrahydrolipstatin]] | [[Category: Tetrahydrolipstatin]] | ||
[[Category: Thioesaterse domain]] | [[Category: Thioesaterse domain]] | ||
| - | + | [[Category: Transferase]] | |
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Revision as of 21:59, 7 January 2013
Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat
Template:ABSTRACT PUBMED 17618296
About this Structure
2px6 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Pemble CW 4th, Johnson LC, Kridel SJ, Lowther WT. Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat. Nat Struct Mol Biol. 2007 Aug;14(8):704-9. Epub 2007 Jul 8. PMID:17618296 doi:10.1038/nsmb1265
