This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1uwh
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:1uwh.png|left|200px]] | [[Image:1uwh.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_1uwh", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_1uwh| PDB=1uwh | SCENE= }} | {{STRUCTURE_1uwh| PDB=1uwh | SCENE= }} | ||
| - | === | + | ===The complex of wild type B-RAF and BAY439006=== |
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_15035987}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 15035987 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_15035987}} | {{ABSTRACT_PUBMED_15035987}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1uwh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UWH OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015035987</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Barford, D.]] | [[Category: Barford, D.]] | ||
| + | [[Category: Project, Cancer Genome]] | ||
[[Category: Roe, S M.]] | [[Category: Roe, S M.]] | ||
[[Category: Wan, P T.C.]] | [[Category: Wan, P T.C.]] | ||
| - | [[Category: | + | [[Category: Transferase]] |
| - | + | ||
| - | + | ||
Revision as of 06:31, 3 October 2012
| |||||||||
| 1uwh, resolution 2.95Å () | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Ligands: | , | ||||||||
| Related: | 1uwj | ||||||||
| |||||||||
| |||||||||
| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
The complex of wild type B-RAF and BAY439006
Template:ABSTRACT PUBMED 15035987
About this Structure
1uwh is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Wan PT, Garnett MJ, Roe SM, Lee S, Niculescu-Duvaz D, Good VM, Jones CM, Marshall CJ, Springer CJ, Barford D, Marais R. Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. Cell. 2004 Mar 19;116(6):855-67. PMID:15035987

