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1yrs

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==About this Structure==
==About this Structure==
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1YRS is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YRS OCA].
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1YRS is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YRS OCA].
==Reference==
==Reference==
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[[Category: Cell cycle]]
[[Category: Cell cycle]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 08:57:08 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 23 13:25:29 2010''

Revision as of 11:25, 23 February 2010

Image:1yrs.png


PDB ID 1yrs

Drag the structure with the mouse to rotate
1yrs, resolution 2.50Å ()
Ligands: , ,
Gene: KIF11, EG5, KNSL1 (Homo sapiens)
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



Crystal structure of KSP in complex with inhibitor 1

Template:ABSTRACT PUBMED 15808464

About this Structure

1YRS is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Cox CD, Breslin MJ, Mariano BJ, Coleman PJ, Buser CA, Walsh ES, Hamilton K, Huber HE, Kohl NE, Torrent M, Yan Y, Kuo LC, Hartman GD. Kinesin spindle protein (KSP) inhibitors. Part 1: The discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP. Bioorg Med Chem Lett. 2005 Apr 15;15(8):2041-5. PMID:15808464 doi:10.1016/j.bmcl.2005.02.055

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