1jut
From Proteopedia
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===E. coli Thymidylate Synthase Bound to dUMP and LY338529, A Pyrrolo(2,3-d)pyrimidine-based Antifolate=== | ===E. coli Thymidylate Synthase Bound to dUMP and LY338529, A Pyrrolo(2,3-d)pyrimidine-based Antifolate=== | ||
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{{ABSTRACT_PUBMED_11697906}} | {{ABSTRACT_PUBMED_11697906}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1jut]] is a 2 chain structure of [[Thymidylate synthase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUT OCA]. | |
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| + | ==See Also== | ||
| + | *[[Thymidylate synthase|Thymidylate synthase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:011697906</ref><references group="xtra"/> |
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Thymidylate synthase]] | [[Category: Thymidylate synthase]] | ||
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[[Category: Drug resistance]] | [[Category: Drug resistance]] | ||
[[Category: Dtmp synthesis]] | [[Category: Dtmp synthesis]] | ||
| - | + | [[Category: Transferase]] | |
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Revision as of 12:14, 26 July 2012
Contents |
E. coli Thymidylate Synthase Bound to dUMP and LY338529, A Pyrrolo(2,3-d)pyrimidine-based Antifolate
Template:ABSTRACT PUBMED 11697906
About this Structure
1jut is a 2 chain structure of Thymidylate synthase with sequence from Escherichia coli. Full crystallographic information is available from OCA.
See Also
Reference
- Sayre PH, Finer-Moore JS, Fritz TA, Biermann D, Gates SB, MacKellar WC, Patel VF, Stroud RM. Multi-targeted antifolates aimed at avoiding drug resistance form covalent closed inhibitory complexes with human and Escherichia coli thymidylate synthases. J Mol Biol. 2001 Nov 2;313(4):813-29. PMID:11697906 doi:10.1006/jmbi.2001.5074
