2ra0
From Proteopedia
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{{STRUCTURE_2ra0| PDB=2ra0 | SCENE= }} | {{STRUCTURE_2ra0| PDB=2ra0 | SCENE= }} | ||
===X-ray Structure of FXa in complex with 7-fluoroindazole=== | ===X-ray Structure of FXa in complex with 7-fluoroindazole=== | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Factor X deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227600 227600]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2ra0]] is a 2 chain structure of [[Factor Xa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RA0 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Factor Xa|Factor Xa]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018159923</ref><references group="xtra"/> |
[[Category: Coagulation factor Xa]] | [[Category: Coagulation factor Xa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Abad, M C.]] | [[Category: Abad, M C.]] | ||
[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
| - | [[Category: Calcium]] | ||
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
[[Category: Egf-like domain]] | [[Category: Egf-like domain]] | ||
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[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Hydroxylation]] | [[Category: Hydroxylation]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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Revision as of 12:49, 26 July 2012
Contents |
X-ray Structure of FXa in complex with 7-fluoroindazole
Template:ABSTRACT PUBMED 18159923
About this Structure
2ra0 is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Lee YK, Parks DJ, Lu T, Thieu TV, Markotan T, Pan W, McComsey DF, Milkiewicz KL, Crysler CS, Ninan N, Abad MC, Giardino EC, Maryanoff BE, Damiano BP, Player MR. 7-fluoroindazoles as potent and selective inhibitors of factor Xa. J Med Chem. 2008 Jan 24;51(2):282-97. Epub 2007 Dec 27. PMID:18159923 doi:10.1021/jm701217r
