1yw9

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===h-MetAP2 complexed with A849519===
===h-MetAP2 complexed with A849519===
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{{ABSTRACT_PUBMED_16789740}}
==About this Structure==
==About this Structure==
1YW9 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YW9 OCA].
1YW9 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YW9 OCA].
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==Reference==
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<ref group="xtra">PMID:16789740</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Methionyl aminopeptidase]]
[[Category: Methionyl aminopeptidase]]
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[[Category: Hydrolase]]
[[Category: Hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 09:34:43 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 13 10:08:27 2009''

Revision as of 07:08, 13 May 2009

Image:1yw9.png

Template:STRUCTURE 1yw9

h-MetAP2 complexed with A849519

Template:ABSTRACT PUBMED 16789740

About this Structure

1YW9 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Sheppard GS, Wang J, Kawai M, Fidanze SD, BaMaung NY, Erickson SA, Barnes DM, Tedrow JS, Kolaczkowski L, Vasudevan A, Park DC, Wang GT, Sanders WJ, Mantei RA, Palazzo F, Tucker-Garcia L, Lou P, Zhang Q, Park CH, Kim KH, Petros A, Olejniczak E, Nettesheim D, Hajduk P, Henkin J, Lesniewski R, Davidsen SK, Bell RL. Discovery and optimization of anthranilic acid sulfonamides as inhibitors of methionine aminopeptidase-2: a structural basis for the reduction of albumin binding. J Med Chem. 2006 Jun 29;49(13):3832-49. PMID:16789740 doi:10.1021/jm0601001

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