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Template:STRUCTURE 1hvy

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{{Structure
{{Structure
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|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1hvy]], resolution 1.90&Aring; (<scene name='initialview01'>default scene</scene>)}}}
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|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1hvy]], [[Resolution|resolution]] 1.90&Aring; (<scene name='initialview01'>default scene</scene>)}}}
|LIGAND= <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=D16:TOMUDEX'>D16</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene>
|LIGAND= <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=D16:TOMUDEX'>D16</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00351 TS_Pyrimidine_HMase]</span>
 
|NONSTDRES=<scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>
|NONSTDRES=<scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hvy OCA], [http://www.ebi.ac.uk/pdbsum/1hvy PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1hvy RCSB]</span>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hvy OCA], [http://www.ebi.ac.uk/pdbsum/1hvy PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1hvy RCSB]</span>
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|PROCESS={{GO|id=GO:0009157 | text = deoxyribonucleoside monophosphate biosynthetic process}}{{GO|id=GO:0006139 | text = nucleobase, nucleoside, nucleotide and nucleic acid metabolic process}}{{GO|id=GO:0048015 | text = phosphoinositide-mediated signaling}}{{GO|id=GO:0009165 | text = nucleotide biosynthetic process}}{{GO|id=GO:0006231 | text = dTMP biosynthetic process}}{{GO|id=GO:0006260 | text = DNA replication}}{{GO|id=GO:0006281 | text = DNA repair}}
|PROCESS={{GO|id=GO:0009157 | text = deoxyribonucleoside monophosphate biosynthetic process}}{{GO|id=GO:0006139 | text = nucleobase, nucleoside, nucleotide and nucleic acid metabolic process}}{{GO|id=GO:0048015 | text = phosphoinositide-mediated signaling}}{{GO|id=GO:0009165 | text = nucleotide biosynthetic process}}{{GO|id=GO:0006231 | text = dTMP biosynthetic process}}{{GO|id=GO:0006260 | text = DNA replication}}{{GO|id=GO:0006281 | text = DNA repair}}
|SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hvyA00 1Hvya00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hvyB00 1Hvyb00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hvyC00 1Hvyc00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hvyD00 1Hvyd00]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR014370 Ipr014370], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000398 Ipr000398]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00303 PF00303]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=41049 d1hvya_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=41050 d1hvyb_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=41051 d1hvyc_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=41052 d1hvyd_]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P04818 P04818]</span>
|SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hvyA00 1Hvya00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hvyB00 1Hvyb00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hvyC00 1Hvyc00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hvyD00 1Hvyd00]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR014370 Ipr014370], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000398 Ipr000398]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00303 PF00303]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=41049 d1hvya_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=41050 d1hvyb_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=41051 d1hvyc_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=41052 d1hvyd_]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P04818 P04818]</span>
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|FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=TYMS TYMS]</span>
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|uPDB=1HVY|CONSURF={{!}}-
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|CONSURF={{!}}-
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{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"

Revision as of 13:43, 26 July 2012

Drag the structure with the mouse to rotate
1hvy, resolution 1.90Å ()
Ligands: , ,
Non-Standard Residues:
Activity: Thymidylate synthase, with EC number 2.1.1.45
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml


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