2f7e
From Proteopedia
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{{STRUCTURE_2f7e| PDB=2f7e | SCENE= }} | {{STRUCTURE_2f7e| PDB=2f7e | SCENE= }} | ||
===PKA complexed with (S)-2-(1H-Indol-3-yl)-1-(5-isoquinolin-6-yl-pyridin-3-yloxymethyl-etylamine=== | ===PKA complexed with (S)-2-(1H-Indol-3-yl)-1-(5-isoquinolin-6-yl-pyridin-3-yloxymethyl-etylamine=== | ||
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{{ABSTRACT_PUBMED_16413780}} | {{ABSTRACT_PUBMED_16413780}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2f7e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F7E OCA]. | |
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| + | ==See Also== | ||
| + | *[[CAMP-dependent protein kinase|CAMP-dependent protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016413780</ref><references group="xtra"/> |
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
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[[Category: Akt inhibitor]] | [[Category: Akt inhibitor]] | ||
[[Category: Protein kinase some]] | [[Category: Protein kinase some]] | ||
| - | + | [[Category: Transferase]] | |
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Revision as of 10:38, 7 January 2013
Contents |
PKA complexed with (S)-2-(1H-Indol-3-yl)-1-(5-isoquinolin-6-yl-pyridin-3-yloxymethyl-etylamine
Template:ABSTRACT PUBMED 16413780
About this Structure
2f7e is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
See Also
Reference
- Li Q, Woods KW, Thomas S, Zhu GD, Packard G, Fisher J, Li T, Gong J, Dinges J, Song X, Abrams J, Luo Y, Johnson EF, Shi Y, Liu X, Klinghofer V, Des Jong R, Oltersdorf T, Stoll VS, Jakob CG, Rosenberg SH, Giranda VL. Synthesis and structure-activity relationship of 3,4'-bispyridinylethylenes: discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer. Bioorg Med Chem Lett. 2006 Apr 1;16(7):2000-7. Epub 2006 Jan 18. PMID:16413780 doi:10.1016/j.bmcl.2005.12.065
