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2r43

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[[Image:2r43.png|left|200px]]
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{{STRUCTURE_2r43| PDB=2r43 | SCENE= }}
{{STRUCTURE_2r43| PDB=2r43 | SCENE= }}
===I50V HIV-1 protease in complex with an amino decorated pyrrolidine-based inhibitor===
===I50V HIV-1 protease in complex with an amino decorated pyrrolidine-based inhibitor===
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{{ABSTRACT_PUBMED_18692068}}
{{ABSTRACT_PUBMED_18692068}}
==About this Structure==
==About this Structure==
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2R43 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R43 OCA].
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[[2r43]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R43 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:18692068</ref><references group="xtra"/>
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<ref group="xtra">PMID:018692068</ref><references group="xtra"/>
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Protein-ligand complex]]
[[Category: Protein-ligand complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 10:40:46 2009''
 

Revision as of 18:44, 7 January 2013

Template:STRUCTURE 2r43

I50V HIV-1 protease in complex with an amino decorated pyrrolidine-based inhibitor

Template:ABSTRACT PUBMED 18692068

About this Structure

2r43 is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Bottcher J, Blum A, Heine A, Diederich WE, Klebe G. Structural and kinetic analysis of pyrrolidine-based inhibitors of the drug-resistant Ile84Val mutant of HIV-1 protease. J Mol Biol. 2008 Nov 7;383(2):347-57. Epub 2008 Jul 29. PMID:18692068 doi:10.1016/j.jmb.2008.07.062

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