1m2z
From Proteopedia
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===Crystal structure of a dimer complex of the human glucocorticoid receptor ligand-binding domain bound to dexamethasone and a TIF2 coactivator motif=== | ===Crystal structure of a dimer complex of the human glucocorticoid receptor ligand-binding domain bound to dexamethasone and a TIF2 coactivator motif=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1m2z]] is a 4 chain structure of [[Glucocorticoid receptor]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M2Z OCA]. | |
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| + | ==See Also== | ||
| + | *[[Glucocorticoid receptor|Glucocorticoid receptor]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:012151000</ref><ref group="xtra">PMID:019756040</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Apolito, C J.]] | [[Category: Apolito, C J.]] | ||
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[[Category: Glucocorticoid receptor]] | [[Category: Glucocorticoid receptor]] | ||
[[Category: Hormone binding pocket]] | [[Category: Hormone binding pocket]] | ||
| + | [[Category: Hormone-hormone activator complex]] | ||
[[Category: Tif2]] | [[Category: Tif2]] | ||
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Revision as of 14:34, 26 July 2012
Contents |
Crystal structure of a dimer complex of the human glucocorticoid receptor ligand-binding domain bound to dexamethasone and a TIF2 coactivator motif
Template:ABSTRACT PUBMED 12151000
About this Structure
1m2z is a 4 chain structure of Glucocorticoid receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Bledsoe RK, Montana VG, Stanley TB, Delves CJ, Apolito CJ, McKee DD, Consler TG, Parks DJ, Stewart EL, Willson TM, Lambert MH, Moore JT, Pearce KH, Xu HE. Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition. Cell. 2002 Jul 12;110(1):93-105. PMID:12151000
- Worth CL, Gong S, Blundell TL. Structural and functional constraints in the evolution of protein families. Nat Rev Mol Cell Biol. 2009 Oct;10(10):709-20. Epub 2009 Sep 16. PMID:19756040 doi:10.1038/nrm2762
Categories: Homo sapiens | Apolito, C J. | Bledsoe, R B. | Consler, T G. | Delves, C J. | Lambert, M H. | Mckee, D D. | Montana, V G. | Moore, J T. | Parks, D J. | Pearce, K H. | Stanley, T B. | Stewart, E L. | Willson, T M. | Xu, H E. | Charge clamp | Coactivator | Dexamethasone | Dimer interface | Glucocorticoid receptor | Hormone binding pocket | Hormone-hormone activator complex | Tif2
