Template:STRUCTURE 1h2l

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{{Structure
{{Structure
|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1h2l]], resolution 2.25&Aring; (<scene name='initialview01'>default scene</scene>)}}}
|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1h2l]], resolution 2.25&Aring; (<scene name='initialview01'>default scene</scene>)}}}
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|SITE= <scene name='pdbsite=FE1:So4+Binding+Site+For+Chain+A'>FE1</scene>
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|SITE= <scene name='pdbsite=AC1:Binding+Site+For+Residue+Fe2+A+1350'>AC1</scene>, <scene name='pdbsite=AC2:Binding+Site+For+Residue+So4+A+1352'>AC2</scene>, <scene name='pdbsite=AC3:Binding+Site+For+Residue+So4+A+1353'>AC3</scene> and <scene name='pdbsite=AC4:Binding+Site+For+Residue+Akg+A+1351'>AC4</scene>
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|LIGAND= <scene name='pdbligand=AKG:2-OXYGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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|LIGAND= <scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam08007 Cupin_4], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam08778 HIF-1a_CTAD]</span>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam08007 Cupin_4], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam08778 HIF-1a_CTAD]</span>
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|RELATEDENTRY=[[1d7g|1d7g]], [[1h2k|1h2k]], [[1h2m|1h2m]], [[1h2n|1h2n]], [[1l8c|1l8c]], [[1lm8|1lm8]], [[1lqb|1lqb]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h2l OCA], [http://www.ebi.ac.uk/pdbsum/1h2l PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1h2l RCSB]</span>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h2l OCA], [http://www.ebi.ac.uk/pdbsum/1h2l PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1h2l RCSB]</span>
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|FUNCTION={{GO|id=GO:0004597 | text = peptide-aspartate beta-dioxygenase activity}}{{GO|id=GO:0005506 | text = iron ion binding}}{{GO|id=GO:0016491 | text = oxidoreductase activity}}{{GO|id=GO:0046872 | text = metal ion binding}}{{GO|id=GO:0016702 | text = oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen}}{{GO|id=GO:0005515 | text = protein binding}}{{GO|id=GO:0004871 | text = signal transducer activity}}{{GO|id=GO:0030528 | text = transcription regulator activity}}{{GO|id=GO:0003705 | text = RNA polymerase II transcription factor activity, enhancer binding}}{{GO|id=GO:0046982 | text = protein heterodimerization activity}}{{GO|id=GO:0003700 | text = transcription factor activity}}{{GO|id=GO:0003677 | text = DNA binding}}{{GO|id=GO:0035035 | text = histone acetyltransferase binding}}
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|SARESOURCES=<span class='plainlinks'>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR003347 Ipr003347], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR013109 Ipr013109], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001321 Ipr001321], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001610 Ipr001610], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR013655 Ipr013655], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR013767 Ipr013767], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR014887 Ipr014887], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001092 Ipr001092], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000014 Ipr000014], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR011598 Ipr011598]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF08007 PF08007], [http://pfam.sanger.ac.uk/family?acc=PF08778 PF08778]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=76574 d1h2la_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=76575 d1h2ls_]<br>UniProt : [http://www.uniprot.org/uniprot/Q9NWT6 Q9NWT6], [http://www.uniprot.org/uniprot/Q16665 Q16665]</span>
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|PROCESS={{GO|id=GO:0006355 | text = regulation of transcription, DNA-dependent}}{{GO|id=GO:0006350 | text = transcription}}{{GO|id=GO:0006950 | text = response to stress}}{{GO|id=GO:0045941 | text = positive regulation of transcription}}{{GO|id=GO:0001666 | text = response to hypoxia}}{{GO|id=GO:0042592 | text = homeostatic process}}{{GO|id=GO:0007165 | text = signal transduction}}{{GO|id=GO:0006351 | text = transcription, DNA-dependent}}{{GO|id=GO:0045449 | text = regulation of transcription}}
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|COMPONENT={{GO|id=GO:0005634 | text = nucleus}}{{GO|id=GO:0005737 | text = cytoplasm}}
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|SARESOURCES=<span class='plainlinks'>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR003347 Ipr003347], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001092 Ipr001092], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001321 Ipr001321], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001610 Ipr001610], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000014 Ipr000014], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR011598 Ipr011598], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR013655 Ipr013655], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR014887 Ipr014887], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000700 Ipr000700]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF08778 PF08778]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=76574 d1h2la_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=76575 d1h2ls_]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?Q9NWT6 Q9NWT6], [http://ca.expasy.org/cgi-bin/niceprot.pl?Q16665 Q16665]</span>
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|FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=HIF1AN HIF1AN], [http://www.genecards.org/cgi-bin/carddisp.pl?id=HIF1A HIF1A]</span>
|FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=HIF1AN HIF1AN], [http://www.genecards.org/cgi-bin/carddisp.pl?id=HIF1A HIF1A]</span>
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|CONSURF={{!}}-
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|uPDB=1H2L|CONSURF={{!}}-
{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"

Revision as of 07:09, 23 December 2009

Drag the structure with the mouse to rotate
1h2l, resolution 2.25Å ()
Sites: , , and
Ligands: , ,
Domains: Cupin_4, HIF-1a_CTAD
Related: 1d7g, 1h2k, 1h2m, 1h2n, 1l8c, 1lm8, 1lqb
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml


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