3cow
From Proteopedia
(Difference between revisions)
Line 1: | Line 1: | ||
- | {{Seed}} | ||
[[Image:3cow.png|left|200px]] | [[Image:3cow.png|left|200px]] | ||
- | <!-- | ||
- | The line below this paragraph, containing "STRUCTURE_3cow", creates the "Structure Box" on the page. | ||
- | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
- | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
- | or leave the SCENE parameter empty for the default display. | ||
- | --> | ||
{{STRUCTURE_3cow| PDB=3cow | SCENE= }} | {{STRUCTURE_3cow| PDB=3cow | SCENE= }} | ||
Line 14: | Line 7: | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[3cow]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3COW OCA]. | |
+ | |||
+ | ==See Also== | ||
+ | *[[Pantothenate synthetase|Pantothenate synthetase]] | ||
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018821554</ref><ref group="xtra">PMID:018424798</ref><references group="xtra"/> |
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Pantoate--beta-alanine ligase]] | [[Category: Pantoate--beta-alanine ligase]] | ||
Line 25: | Line 21: | ||
[[Category: Ciulli, A.]] | [[Category: Ciulli, A.]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
- | [[Category: Cytoplasm]] | ||
[[Category: Drug design]] | [[Category: Drug design]] | ||
[[Category: Enzyme]] | [[Category: Enzyme]] | ||
Line 35: | Line 30: | ||
[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Pantothenate biosynthesis]] | [[Category: Pantothenate biosynthesis]] | ||
- | |||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 10:47:50 2009'' |
Revision as of 18:52, 7 January 2013
Contents |
Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.8 Ang resolution- in complex with sulphonamide inhibitor 2
About this Structure
3cow is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
See Also
Reference
- Ciulli A, Scott DE, Ando M, Reyes F, Saldanha SA, Tuck KL, Chirgadze DY, Blundell TL, Abell C. Inhibition of Mycobacterium tuberculosis pantothenate synthetase by analogues of the reaction intermediate. Chembiochem. 2008 Nov 3;9(16):2606-11. PMID:18821554 doi:10.1002/cbic.200800437
- Moure CM, Gimble FS, Quiocho FA. Crystal structures of I-SceI complexed to nicked DNA substrates: snapshots of intermediates along the DNA cleavage reaction pathway. Nucleic Acids Res. 2008 Jun;36(10):3287-96. Epub 2008 Apr 19. PMID:18424798 doi:10.1093/nar/gkn178