3cow

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[[Image:3cow.png|left|200px]]
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{{STRUCTURE_3cow| PDB=3cow | SCENE= }}
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==About this Structure==
==About this Structure==
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3COW is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3COW OCA].
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[[3cow]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3COW OCA].
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==See Also==
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*[[Pantothenate synthetase|Pantothenate synthetase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:18821554</ref><references group="xtra"/>
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<ref group="xtra">PMID:018821554</ref><ref group="xtra">PMID:018424798</ref><references group="xtra"/>
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Pantoate--beta-alanine ligase]]
[[Category: Pantoate--beta-alanine ligase]]
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[[Category: Ciulli, A.]]
[[Category: Ciulli, A.]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
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[[Category: Cytoplasm]]
 
[[Category: Drug design]]
[[Category: Drug design]]
[[Category: Enzyme]]
[[Category: Enzyme]]
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[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Pantothenate biosynthesis]]
[[Category: Pantothenate biosynthesis]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 10:47:50 2009''
 

Revision as of 18:52, 7 January 2013

Template:STRUCTURE 3cow

Contents

Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.8 Ang resolution- in complex with sulphonamide inhibitor 2

About this Structure

3cow is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

See Also

Reference

  • Ciulli A, Scott DE, Ando M, Reyes F, Saldanha SA, Tuck KL, Chirgadze DY, Blundell TL, Abell C. Inhibition of Mycobacterium tuberculosis pantothenate synthetase by analogues of the reaction intermediate. Chembiochem. 2008 Nov 3;9(16):2606-11. PMID:18821554 doi:10.1002/cbic.200800437
  • Moure CM, Gimble FS, Quiocho FA. Crystal structures of I-SceI complexed to nicked DNA substrates: snapshots of intermediates along the DNA cleavage reaction pathway. Nucleic Acids Res. 2008 Jun;36(10):3287-96. Epub 2008 Apr 19. PMID:18424798 doi:10.1093/nar/gkn178

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