1mu6

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[[Image:1mu6.png|left|200px]]
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==About this Structure==
==About this Structure==
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1MU6 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MU6 OCA].
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[[1mu6]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MU6 OCA].
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==See Also==
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*[[Hirudin]]
==Reference==
==Reference==
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[[Category: Coburn, C A.]]
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[[Category: Detwiler, T J.]]
[[Category: Dorsey, B D.]]
[[Category: Dorsey, B D.]]
[[Category: Gardell, S J.]]
[[Category: Gardell, S J.]]
[[Category: Holahan, M A.]]
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[[Category: Lynch, J J.]]
[[Category: McDonough, C M.]]
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[[Category: McMasters, D R.]]
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[[Category: Blood clotting]]
[[Category: Blood clotting]]
[[Category: Hydrolase]]
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[[Category: Hydrolase/blood clotting complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 11:00:04 2009''
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Revision as of 20:42, 26 December 2010

Template:STRUCTURE 1mu6

Contents

Crystal Structure of Thrombin in Complex with L-378,622

Template:ABSTRACT PUBMED 12570369

About this Structure

1mu6 is a 3 chain structure of Hirudin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Burgey CS, Robinson KA, Lyle TA, Sanderson PE, Lewis SD, Lucas BJ, Krueger JA, Singh R, Miller-Stein C, White RB, Wong B, Lyle EA, Williams PD, Coburn CA, Dorsey BD, Barrow JC, Stranieri MT, Holahan MA, Sitko GR, Cook JJ, McMasters DR, McDonough CM, Sanders WM, Wallace AA, Clayton FC, Bohn D, Leonard YM, Detwiler TJ Jr, Lynch JJ Jr, Yan Y, Chen Z, Kuo L, Gardell SJ, Shafer JA, Vacca JP. Metabolism-directed optimization of 3-aminopyrazinone acetamide thrombin inhibitors. Development of an orally bioavailable series containing P1 and P3 pyridines. J Med Chem. 2003 Feb 13;46(4):461-73. PMID:12570369 doi:http://dx.doi.org/10.1021/jm020311f

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