2iim

From Proteopedia

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[[Category: Romir, J.]]
[[Category: Romir, J.]]
[[Category: Beta-barrel]]
[[Category: Beta-barrel]]
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[[Category: Signaling protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 19:56:11 2009''

Revision as of 16:56, 10 June 2009

Template:STRUCTURE 2iim

Contents

SH3 Domain of Human Lck

Template:ABSTRACT PUBMED 17118402

Disease

Known disease associated with this structure: SCID due to LCK deficiency OMIM:[153390]

About this Structure

2IIM is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Romir J, Lilie H, Egerer-Sieber C, Bauer F, Sticht H, Muller YA. Crystal structure analysis and solution studies of human Lck-SH3; zinc-induced homodimerization competes with the binding of proline-rich motifs. J Mol Biol. 2007 Feb 2;365(5):1417-28. Epub 2006 Oct 21. PMID:17118402 doi:10.1016/j.jmb.2006.10.058

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