2pr3
From Proteopedia
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[[Image:2pr3.png|left|200px]] | [[Image:2pr3.png|left|200px]] | ||
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{{STRUCTURE_2pr3| PDB=2pr3 | SCENE= }} | {{STRUCTURE_2pr3| PDB=2pr3 | SCENE= }} | ||
===Factor XA inhibitor=== | ===Factor XA inhibitor=== | ||
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{{ABSTRACT_PUBMED_17581239}} | {{ABSTRACT_PUBMED_17581239}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Factor X deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227600 227600]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2pr3]] is a 2 chain structure of [[Factor Xa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PR3 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Factor Xa|Factor Xa]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017581239</ref><references group="xtra"/> |
[[Category: Coagulation factor Xa]] | [[Category: Coagulation factor Xa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Blood clotting]] | [[Category: Blood clotting]] | ||
[[Category: Fxa coagulation factor inhibitor]] | [[Category: Fxa coagulation factor inhibitor]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 11:10:34 2009'' | ||
Revision as of 15:10, 26 July 2012
Contents |
Factor XA inhibitor
Template:ABSTRACT PUBMED 17581239
About this Structure
2pr3 is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Van Huis CA, Bigge CF, Casimiro-Garcia A, Cody WL, Dudley DA, Filipski KJ, Heemstra RJ, Kohrt JT, Narasimhan LS, Schaum RP, Zhang E, Bryant JW, Haarer S, Janiczek N, Leadley RJ Jr, McClanahan T, Thomas Peterson J, Welch KM, Edmunds JJ. Structure-based drug design of pyrrolidine-1, 2-dicarboxamides as a novel series of orally bioavailable factor Xa inhibitors. Chem Biol Drug Des. 2007 Jun;69(6):444-50. PMID:17581239 doi:10.1111/j.1747-0285.2007.00520.x
