2gtw
From Proteopedia
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[[Image:2gtw.png|left|200px]] | [[Image:2gtw.png|left|200px]] | ||
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{{STRUCTURE_2gtw| PDB=2gtw | SCENE= }} | {{STRUCTURE_2gtw| PDB=2gtw | SCENE= }} | ||
===Human Class I MHC HLA-A2 in complex with the nonameric Melan-A/MART-1(27-35) peptide having A27L substitution=== | ===Human Class I MHC HLA-A2 in complex with the nonameric Melan-A/MART-1(27-35) peptide having A27L substitution=== | ||
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{{ABSTRACT_PUBMED_17719062}} | {{ABSTRACT_PUBMED_17719062}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Abacavir hypersensitivity, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=142800 142800]], Ankylosing spondylitis, susceptibility to, 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=142800 142800]], Stevens-Johnson syndrome, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=142800 142800]], Hypoproteinemia, hypercatabolic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=109700 109700]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2gtw]] is a 6 chain structure of [[Beta-2 microglobulin]] and [[Major histocompatibility complex]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GTW OCA]. | |
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| + | ==See Also== | ||
| + | *[[Beta-2 microglobulin|Beta-2 microglobulin]] | ||
| + | *[[Major histocompatibility complex|Major histocompatibility complex]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017719062</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Baker, B M.]] | [[Category: Baker, B M.]] | ||
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[[Category: Cancer vaccine]] | [[Category: Cancer vaccine]] | ||
[[Category: Hla-a2]] | [[Category: Hla-a2]] | ||
| + | [[Category: Immune system]] | ||
[[Category: Melan-a/mart-1 peptide]] | [[Category: Melan-a/mart-1 peptide]] | ||
[[Category: Melanoma]] | [[Category: Melanoma]] | ||
[[Category: Mhc class i]] | [[Category: Mhc class i]] | ||
[[Category: Nonapeptide]] | [[Category: Nonapeptide]] | ||
| - | [[Category: X-ray crystallography]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 11:19:02 2009'' | ||
Revision as of 15:23, 26 July 2012
Contents |
Human Class I MHC HLA-A2 in complex with the nonameric Melan-A/MART-1(27-35) peptide having A27L substitution
Template:ABSTRACT PUBMED 17719062
About this Structure
2gtw is a 6 chain structure of Beta-2 microglobulin and Major histocompatibility complex with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Borbulevych OY, Insaidoo FK, Baxter TK, Powell DJ Jr, Johnson LA, Restifo NP, Baker BM. Structures of MART-126/27-35 Peptide/HLA-A2 complexes reveal a remarkable disconnect between antigen structural homology and T cell recognition. J Mol Biol. 2007 Oct 5;372(5):1123-36. Epub 2007 Jul 26. PMID:17719062 doi:10.1016/j.jmb.2007.07.025
