2hvx
From Proteopedia
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{{STRUCTURE_2hvx| PDB=2hvx | SCENE= }} | {{STRUCTURE_2hvx| PDB=2hvx | SCENE= }} | ||
===Discovery of Potent, Orally Active, Nonpeptide Inhibitors of Human Mast Cell Chymase by Using Structure-Based Drug Design=== | ===Discovery of Potent, Orally Active, Nonpeptide Inhibitors of Human Mast Cell Chymase by Using Structure-Based Drug Design=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2hvx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HVX OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017361995</ref><references group="xtra"/> |
[[Category: Chymase]] | [[Category: Chymase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Wang, Y.]] | [[Category: Wang, Y.]] | ||
[[Category: Wells, G I.]] | [[Category: Wells, G I.]] | ||
| + | [[Category: Hydrolase]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 11:34:25 2009'' | ||
Revision as of 11:59, 7 January 2013
Discovery of Potent, Orally Active, Nonpeptide Inhibitors of Human Mast Cell Chymase by Using Structure-Based Drug Design
Template:ABSTRACT PUBMED 17361995
About this Structure
2hvx is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Greco MN, Hawkins MJ, Powell ET, Almond HR Jr, de Garavilla L, Hall J, Minor LK, Wang Y, Corcoran TW, Di Cera E, Cantwell AM, Savvides SN, Damiano BP, Maryanoff BE. Discovery of potent, selective, orally active, nonpeptide inhibitors of human mast cell chymase. J Med Chem. 2007 Apr 19;50(8):1727-30. Epub 2007 Mar 16. PMID:17361995 doi:10.1021/jm0700619
