3ela
From Proteopedia
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[[Image:3ela.png|left|200px]] | [[Image:3ela.png|left|200px]] | ||
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{{STRUCTURE_3ela| PDB=3ela | SCENE= }} | {{STRUCTURE_3ela| PDB=3ela | SCENE= }} | ||
===Crystal structure of active site inhibited coagulation factor VIIA mutant in complex with soluble tissue factor=== | ===Crystal structure of active site inhibited coagulation factor VIIA mutant in complex with soluble tissue factor=== | ||
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{{ABSTRACT_PUBMED_18640965}} | {{ABSTRACT_PUBMED_18640965}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Factor VII deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]], Myocardial infarction, decreased susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3ela]] is a 3 chain structure of [[Factor VIIa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ELA OCA]. | |
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| + | ==See Also== | ||
| + | *[[Factor VIIa|Factor VIIa]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018640965</ref><references group="xtra"/> |
[[Category: Coagulation factor VIIa]] | [[Category: Coagulation factor VIIa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Fodje, M.]] | [[Category: Fodje, M.]] | ||
[[Category: Svensson, L A.]] | [[Category: Svensson, L A.]] | ||
| - | [[Category: Allosteric regulation]] | ||
| - | [[Category: Allostery]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Blood clotting]] | [[Category: Blood clotting]] | ||
| - | [[Category: | + | [[Category: Hydrolase-hydrolase inhibitor complex]] |
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[[Category: Serine protease]] | [[Category: Serine protease]] | ||
| - | [[Category: Transmembrane]] | ||
| - | [[Category: Zymogen]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:17:26 2009'' | ||
Revision as of 16:44, 26 July 2012
Contents |
Crystal structure of active site inhibited coagulation factor VIIA mutant in complex with soluble tissue factor
Template:ABSTRACT PUBMED 18640965
About this Structure
3ela is a 3 chain structure of Factor VIIa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Bjelke JR, Olsen OH, Fodje M, Svensson LA, Bang S, Bolt G, Kragelund BB, Persson E. Mechanism of the Ca2+-induced enhancement of the intrinsic factor VIIa activity. J Biol Chem. 2008 Sep 19;283(38):25863-70. Epub 2008 Jul 17. PMID:18640965 doi:10.1074/jbc.M800841200
