2o8c
From Proteopedia
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===human MutSalpha (MSH2/MSH6) bound to ADP and an O6-methyl-guanine T mispair=== | ===human MutSalpha (MSH2/MSH6) bound to ADP and an O6-methyl-guanine T mispair=== | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Colorectal cancer, hereditary nonpolyposis, type 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=609309 609309]], Mismatch repair cancer syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=609309 609309]], Muir-Torre syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=609309 609309]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2o8c]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O8C OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017531815</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Beese, L S.]] | [[Category: Beese, L S.]] | ||
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[[Category: Warren, J J.]] | [[Category: Warren, J J.]] | ||
[[Category: Cancer]] | [[Category: Cancer]] | ||
| + | [[Category: Dna binding protein-dna complex]] | ||
[[Category: Dna damage response]] | [[Category: Dna damage response]] | ||
[[Category: Dna mismatch repair]] | [[Category: Dna mismatch repair]] | ||
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[[Category: O6-methyl-guanine]] | [[Category: O6-methyl-guanine]] | ||
[[Category: Protein-dna complex]] | [[Category: Protein-dna complex]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:18:44 2009'' | ||
Revision as of 12:48, 7 January 2013
human MutSalpha (MSH2/MSH6) bound to ADP and an O6-methyl-guanine T mispair
Template:ABSTRACT PUBMED 17531815
About this Structure
2o8c is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Warren JJ, Pohlhaus TJ, Changela A, Iyer RR, Modrich PL, Beese LS. Structure of the human MutSalpha DNA lesion recognition complex. Mol Cell. 2007 May 25;26(4):579-92. PMID:17531815 doi:10.1016/j.molcel.2007.04.018
