This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2q8g
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:2q8g.png|left|200px]] | [[Image:2q8g.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_2q8g", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_2q8g| PDB=2q8g | SCENE= }} | {{STRUCTURE_2q8g| PDB=2q8g | SCENE= }} | ||
===Structure of pyruvate dehydrogenase kinase isoform 1 in complex with glucose-lowering drug AZD7545=== | ===Structure of pyruvate dehydrogenase kinase isoform 1 in complex with glucose-lowering drug AZD7545=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_17683942}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 17683942 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_17683942}} | {{ABSTRACT_PUBMED_17683942}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2q8g]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q8G OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Pyruvate dehydrogenase kinase|Pyruvate dehydrogenase kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017683942</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Chuang, D T.]] | [[Category: Chuang, D T.]] | ||
| Line 33: | Line 24: | ||
[[Category: Mitochondrial kinase]] | [[Category: Mitochondrial kinase]] | ||
[[Category: Pyruvate dehydrogenase complex]] | [[Category: Pyruvate dehydrogenase complex]] | ||
| - | + | [[Category: Transferase]] | |
| - | + | ||
Revision as of 20:49, 7 January 2013
Contents |
Structure of pyruvate dehydrogenase kinase isoform 1 in complex with glucose-lowering drug AZD7545
Template:ABSTRACT PUBMED 17683942
About this Structure
2q8g is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Kato M, Li J, Chuang JL, Chuang DT. Distinct structural mechanisms for inhibition of pyruvate dehydrogenase kinase isoforms by AZD7545, dichloroacetate, and radicicol. Structure. 2007 Aug;15(8):992-1004. Epub 2007 Aug 2. PMID:17683942 doi:10.1016/j.str.2007.07.001
